Spravato: A New Hope for Treating Suicidal Ideations
Dr. Rayner graduated from the University of Utah School of Medicine and completed his residency training in adult psychiatry at the University of Nevada, Reno. He is a member of the American Psychiatric Association and the clinical TMS society. He specializes in the prevention, diagnosis, and treatment of mental disorders,... more
Suicidal ideations, or suicidal thoughts, are a common symptom of depression and other mental health conditions. These thoughts can be overwhelming and may lead to suicide attempts if left untreated. Fortunately, there are effective treatments available to help individuals manage suicidal ideations, and Spravato is one of them.
What is Spravato?
Spravato, or esketamine, is a medication approved by the FDA for the treatment of depression that has not responded to other medications. It's a nasal spray that works by targeting the N-methyl-D-aspartate (NMDA) receptor in the brain, which plays a role in regulating mood and emotions. Spravato is administered under the supervision of a healthcare provider and is used in conjunction with an oral antidepressant.
How does Spravato treat suicidal ideations?
Studies have shown that Spravato can help alleviate suicidal ideations in people with treatment-resistant depression. In a clinical trial, participants who received Spravato reported a significant reduction in suicidal thoughts compared to those who received a placebo. The effect of Spravato was observed as early as four hours after treatment and lasted up to four weeks.
Additionally, Spravato can also help alleviate other depressive symptoms, including feelings of sadness, hopelessness, and anxiety. It's important to note that Spravato is not a standalone treatment for depression or suicidal ideations and should be used in conjunction with other therapies, including psychotherapy and medication.
Is Spravato safe?
Like any medication, Spravato has potential side effects. The most common side effects reported during clinical trials include dizziness, nausea, and dissociation, a feeling of detachment from reality. However, these side effects were generally mild to moderate in severity and resolved within a few hours after treatment. Spravato is only available through a restricted distribution program and should only be administered under the supervision of a healthcare provider.
Suicidal ideations can be a debilitating symptom of depression and other mental health conditions. However, effective treatments, such as Spravato, can help manage these thoughts and improve overall quality of life. If you're struggling with suicidal ideations or other symptoms of depression, it's essential to seek help from a healthcare professional.
References:
- Canuso CM, Singh JB, Fedgchin M, et al. Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of Symptoms of Depression and Suicidality in Patients at Imminent Risk for Suicide: Results of a Double-Blind, Randomized, Placebo-Controlled Study. Am J Psychiatry. 2018 Aug 1;175(8):620-630.
- Daly EJ, Singh JB, Fedgchin M, et al. Efficacy and Safety of Intranasal Esketamine Adjunctive to Oral Antidepressant Therapy in Treatment-Resistant Depression: A Randomized Clinical Trial. JAMA Psychiatry. 2018 Nov 1;75(11):139-148.
- Sanacora G, Frye MA, McDonald W, et al. A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders. JAMA Psychiatry. 2017 May 1;74(5):399-405.
If you are struggling with suicidal ideations and are interested in learning more about Spravato or other treatment options, come see us at Whole Mind (www.wholemindtms.com).
