Pediatrician Questions Pediatrician

Can allergy medications cause any serious side effects?

My daughter has an allergy and I want to give her medications. Can allergy medications cause any serious side effects?

1 Answer

Allergy medications, when used as directed and under the guidance of a healthcare professional, are generally safe and well-tolerated for most individuals, including children. However, like all medications, allergy medications can potentially cause side effects, and it's essential to be aware of these potential risks. Serious side effects from allergy medications are rare but can occur in some cases. Here are some considerations regarding potential side effects of allergy medications:

Antihistamines: Common side effects of antihistamines, such as cetirizine (Zyrtec), loratadine (Claritin), and fexofenadine (Allegra), may include drowsiness, dry mouth, headache, dizziness, and stomach upset. Non-sedating antihistamines like loratadine and fexofenadine are less likely to cause drowsiness compared to older antihistamines like diphenhydramine (Benadryl). Serious side effects from antihistamines are rare but can include allergic reactions, rapid heartbeat, and difficulty urinating.

Nasal Corticosteroids: Nasal corticosteroid sprays, such as fluticasone (Flonase) and mometasone (Nasonex), are generally safe and well-tolerated when used as directed. Common side effects may include nasal irritation, nosebleeds, headache, and throat irritation. Rarely, long-term use of nasal corticosteroids may lead to systemic side effects such as adrenal suppression or growth suppression in children, but this is uncommon with standard doses used for allergic rhinitis.

Decongestants: Oral decongestants, such as pseudoephedrine (Sudafed), can cause side effects such as increased heart rate, increased blood pressure, insomnia, nervousness, and irritability. Nasal decongestant sprays, such as oxymetazoline (Afrin), should be used for no more than three days to avoid rebound congestion and potential side effects such as nasal irritation and dryness.

Leukotriene Receptor Antagonists: Montelukast (Singulair) is a leukotriene receptor antagonist used to treat allergic rhinitis and asthma. Common side effects may include headache, stomach upset, fatigue, and mood changes. Rarely, montelukast has been associated with neuropsychiatric side effects such as depression, anxiety, and suicidal thoughts, especially in children and adolescents.

Allergy Eye Drops: Allergy eye drops containing antihistamines or mast cell stabilizers are generally safe and well-tolerated. Common side effects may include temporary stinging or burning sensation in the eyes. Rarely, eye drops containing decongestants may cause rebound redness and irritation with prolonged use.

It's important to use allergy medications as directed and discuss any concerns or potential side effects with your daughter's healthcare provider. They can provide personalized recommendations and monitor for any adverse reactions while your daughter is using allergy medications. If your daughter experiences severe or concerning side effects from allergy medications, seek medical attention promptly.