With these risk factors in mind, we typically employ several agents during the course of an anesthetic to help prevent PONV. These various drugs work at different receptors throughout the body and help prevent the transmission of noxious stimuli to the vomiting center of the brain. Prevention is the best course...some of these drugs are more effective prior to the occurrence of PONV, although we do have several others that work as "rescue" agents. The key is to let your anesthesiologist know ahead of time so that an effective plan can be formulated prior to the administration of the anesthetic.
Avoiding a general anesthetic is the most obvious choice. The use of blocks and spinals (depending on the type of surgery) can help reduce the likelihood of PONV.
If you do need a general, having a Total IV Anesthetic (no anesthetic gas is used here) is the best method to prevent this occurrence. Speak with your anesthesiologist about what options you do have available and see if a TIVA (total IV) is appropriate.
Go into surgery believing that you will do well afterwards. Your mindset is also very important. Don't assume you will have nausea just because it happened before. When you do find a combo that works, jot the details down and ask for it in the future.
Hope this helps. Best of luck to you!