Gene Therapy for Oculopharyngeal Muscular Dystrophy

Some populations are more at risk than others for inheriting the disease. By distribution the disease affects populations in twenty-nine countries across the world, with the highest incidences clustered in the French-Canadian Quebecois population at one in one thousand, the Bukhara Jewish central Asian population of Israel and the Latino population of New Mexico. Reports have also indicated that in Europe the disease is prevalent in the native French population at a one in one hundred thousand occurrence. In all these populations the autosomal dominant inheritance form of the disease is more common than the recessive which is a rare form of inheritance.