Gluten's role in depression
In regard to depression, a study was published in the May 2014 issue of Alimentary Pharmacology and Therapeutics that illustrated the psychological effects of gluten on people who have a sensitivity to wheat. The 22 participants in this study adopted a diet that was free of gluten and FODMAPS during a three-day baseline period. They were then submitted to some dietary challenges where they received edibles that contained either whey, gluten, or a placebo for three days. Afterward, they followed a three-day “washout” period before commencing with the next diet regimen.
At the end of this study, the participants were assessed using the Spielberg State-Trait Personality Inventory. The participants who ingested gluten scored higher for having symptoms depression as compared to those who had the placebo diet.