All of these factors negatively affect the gut's healing process.
These are a lot of confounding factors, but how do all of these slow the healing process? On one end of the spectrum is celiac disease. Celiac disease is an autoimmune condition, which is set off by the exposure to gluten. One of the most common developments seen in the disease is a shrinking and dulling of the intestinal villi. Of course, a patient wouldn’t know that this is happening, so doctors are able to identify this issue in a patient by getting a biopsy of the small intestine. The short intestine is normally 3-5 times shorter in patients with celiac disease than in their non-celiac counterparts.