Sometimes lupus patients develop autoimmune thyroid disease which is not unusual. The work of the thyroid is to help people control their body metabolism. If a thyroid is poorly functioning, it can affect crucial organs such as kidneys, heart, brain, and liver. Also, it can lead to weight loss and weight gain. Other symptoms are dry hair and skin and moodiness. An underactive contribute to the development of hypothyroidism. An overactive thyroid contributes to the development of a condition called hyperthyroidism. Lupus patients can find treatments that help get metabolism back on track.