Success of Lab-Grown Colons Could Transform Future Crohn's and Colitis Research
What this means for the future
The human colon organoids, along with other various parts of the gastrointestinal tract that can be grown by researchers, may also provide a new platform that could serve as the basis for testing new drugs as most oral medications are absorbed into the body through the gut.
References
Cincinnati Children's Hospital Medical Center. (2017, June 22). Lab-grown human colons change study of GI disease: Stem cell derived organoids fill gap in modeling common ailments. ScienceDaily. Retrieved August 28, 2017 from www.sciencedaily.com/releases/2017/06/170622122000.htm
Jorge O. Múnera, Nambirajan Sundaram, Scott A. Rankin, David Hill, Carey Watson, Maxime Mahe, Jefferson E. Vallance, Noah F. Shroyer, Katie L. Sinagoga, Adrian Zarzoso-Lacoste, Jonathan R. Hudson, Jonathan C. Howell, Praneet Chatuvedi, Jason R. Spence, John M. Shannon, Aaron M. Zorn, Michael A. Helmrath, James M. Wells. (2017). Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling. Cell Stem Cell, 2017 DOI: 10.1016/j.stem.2017.05.020
