Possible risks associated with anti-TNF treatment
TNF-inhibitors have also been found to reduce the need for surgery in patients with Crohn's disease. However, there have not been many studies done to monitor the patient's response after their first year of treatment. Researchers Eberhardson and colleagues wanted to study the risk of bowel resection in patients undergoing TNF inhibitor treatment. Specifically, the researchers studied patients to determine if they were more or less likely to undergo bowel resection when remaining on the TNF inhibitor treatment beyond 12 months when compared with patients who ceased treatment after less than 12 months.