1 What is Aminomine?

Brand: Aminomine

Generic: Tryptophan

Aminomine is an essential amino acid which is utilized by the body for the maintenance of normal growth in infants. Nitrogen balance in adults is also maintained by tryptophan. Moreover, tryptophan is needed by the body for synthesis of niacin and serotonin. This cannot be synthesized by the body therefore you should take tryptophan containing foods adequately to prevent its deficiency.

Tryptophan can be found in cheese, chicken, eggs, fish, milk, nuts, peanuts, pumpkin seeds etc. In clinical practices, L-tryptophan is widely used to treat depression, anxiety, premenstrual syndrome, sleep apnea, and many other problems.

L-tryptophan is prescribed along with other medications to treat mental depression. It is also used in combination with Lithium to treat bipolar disorder. This product is available in 500 mg and 1000 mg tablets and capsules.

2 What To Know Before Using

If you are about to start Aminomine, the risks and benefits ratio of taking this medicine should be considered. This is a decision that your doctor will make with your active participation.

Certain factors such as present and past illness, drug interactions, metabolic impairments, hypersensitivity reactions, pregnancy, lactation etc. are considered as they may alter the drug action.

Tryptophan may cause breathing problems in patients with certain types of digestion problems including (e.g. achlorhydria). It also increases the risk of bladder cancer.

Moreover, it can potentiate the development of cataract and diabetes mellitus in patients with a family history of diabetes. Thus, the use of tryptophan should be considered cautiously.

Make sure you tell your doctor if you are allergic to such medications.

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

3 Proper Usage

Medicines should be used following the directions given by a doctor. The dose of Aminomine will vary according to patient’s condition or requirements. You should follow the doctor's directions and advice.

The amount of medicine that you take should not exceed the maximum therapeutic dose. Also, the frequency of your daily drug administration and the duration of drug therapy depend on the particular medical problem for which you are taking the medicine.

It is usually prescribed to take 8 to 12 grams of L-tryptophan orally in divided doses of three or four times a day. As the safety and effective use of tryptophan is not determined in pediatric patients, this drug is rarely used in infants.

This drug should be taken with a low-protein and carbohydrate-rich meal to prevent stomach upset.

Always try to take your medicine in time. If you miss any dose of this medicine, you should take it as soon as possible. But when it is time for your next dose, then skip the missed dose and go back to your regular dosing schedule.

You should store the medicine in a closed container at room temperature away from heat, moisture, and direct light.

4 Precautions To Take

Regular visits are recommended to make sure this medicine is working properly while you are undergoing Aminomine therapy. Some important measures should be taken if you feel any discomfort following this drug therapy.

Tryptophan may cause agitation, confusion, diarrhea, fever, overactive reflexes, restlessness, shivering, sweating, trembling or shaking when it is given beyond safety margin.

If any symptom of tryptophan overdose is noticed, you should get emergency help immediately. Dryness of mouth is a common side effect of tryptophan therapy.

Using sugarless candy or gum or a saliva substitute may be helpful to get rid of such problems. If dry mouth continues for more than 2 weeks, you should consult with your physician immediately.

Excessive exposure to ultraviolet light reduces the chance of cataract formation.

Certain drugs should not be used concurrently with such medications. It is always recommended to consult your doctor if you are in need of some drugs for another health problem.

Sometimes, it is must to avoid some particular medicines during this drug therapy in order to get rid of serious drug reactions. L-tryptophan should be used with caution with other anti-depressants like citalopram, vilazodone, linezolid, desvenlafaxine, and phenelzine.

Concurrent administration of such medications is responsible for excessive serotonin in the brain which increases the risk of a serious condition called serotonin syndrome.

5 Potential Side Effects

There are some unwanted side-effects associated with Aminomine that usually do not need medical attention. These side-effects usually go away during the treatment episode as your body adjusts to the medicine. Additionally, your health care professional may advise you about the ways to prevent or reduce those unwanted side-effects.

Sometimes, you may need to consult with the doctor if you feel any of the toxic effects which are common to all members, but the relative propensity differs.

Some adverse effects of L-tryptophan are nausea, vomiting, headache, dizziness, dry mouth, loss of appetite, and improper sexual behavior.

6 Related Clinical Trials