As with all medicines, the risks must be compared to how much a medication will help you. This is a decision that you and your doctor will make together.
For this medication, there are many things that need to be considered:
Allergies: Inform your doctor if you have ever had an allergic reaction to doxorubicin or to any other medications. It is also important to inform your doctor of any non-medicine allergies such as foods, dyes, preservatives or animals.
Pediatric: No appropriate studies have been performed on the relationship of age to the effects of this medication in children. Safety and efficacy have not been established.
Geriatric: Up-to-date studies have not shown any problems specific to the elderly that would limit the use of this medication in the elderly population.
Pregnancy: This medication is listed as Pregnancy Category D. This means that studies in pregnant women have demonstrated a risk to the unborn child. However, the benefits of this medication in a life-threatening situation or serious disease may outweigh the potential risk.
Breastfeeding: There are no up-to-date studies in women for determining infant risk when using this medication while breastfeeding. Weigh the potential risks with the benefits before taking this medication while breastfeeding.
Drug Interactions: Certain medications should not be used together. However, in certain cases, two medications may be used together, even if an interaction might occur.
In these cases, your doctor may want to change your dose or take other precautions. When taking this medication, it is important that you inform your doctor if you are taking any of the medications listed below.
The following interactions were selected on the basis of potential significance and are not all-inclusive.
Myopia (changes in the eyeball causing vision problems)
Systemic lupus erythematosus (SLE) - Use with caution. May make these conditions worse.
Heart or blood vessel disease - Use with caution. May increase the risk of experiencing chest pain or heart attacks.
3 Proper Usage
This medication should not be the first option to treat your condition. It is meant to be used only after you have tried other medication that has not worked or have caused unwanted side effects.
This medication comes with a patient information brochure. It is very important that your read this information. Ask your doctor if you have any questions.
Along with this medication, treatment for your hypertension may include weight control and changes in your diet, especially eliminating foods high in sodium.
Your doctor will tell you which options are most important for you. Ask your doctor before changing your diet.
Many patients with hypertension will not notice any signs of a problem and many patients feel normal.
It is very important that you take your medication and that you keep your appointments with your doctor, even if you are feeling well.
This medication will not cure your hypertension, but it will help control it. You must continue to take your medication if you expect to lower your blood pressure and keep it down.
You may have to take hypertension medication for the rest of your life. If hypertension is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke or kidney disease.
Take this medication at the same time every day.
Dosing: Different patients will be given a different dose of this medication based on the strength of the medication.
The number of doses you take each day, the time between doses and the length of time you take this medication depends on the reason you are taking this medication.
The following information only includes the average dose of this medication. If your dose is different, do not change it without first speaking to your doctor.
Adults - Your doctor will determine your starting dose as needed and may increase the dose as needed. The dose is not normally more than 300mg of aliskiren and 10mg of amlodipine and 25mg of hydrochlorothiazide once a day.
Children - Use and dose must be determined by your doctor.
Missed dose: If you miss a dose of this medication, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not double dose.
Storage: Store this medication in a closed container at room temperature. Keep it away from heat, moisture, and direct light. Do not freeze. Keep our of the reach of children.
Do not keep expired medication or medication you no longer need. Ask your doctor how to dispose of any medication you do not use.
4 Precautions to Take
It is very important that your doctor checks in with you often while you are receiving this medication to make sure that it is working properly. Blood tests may be needed to check for unwanted effects.
Using this medication while pregnant can harm your unborn child. Use an effective form of birth control to keep from becoming pregnant.
Inform your doctor immediately if you believe you have become pregnant while using this medication.
This medication may cause a condition called angioedema. Inform your doctor immediately if you experience swelling of the face, arms, legs, eyes, lips, tongue or throat, or problems with swallowing and breathing.
Dizziness, lightheadedness or fainting (syncope) may occur after you take this medication, especially when taking a diuretic (water pill). Getting up slowly may lessen this problem.
If you feel dizzy, lie back down so you do not faint. Sit for a few moments before standing to prevent the dizziness or lightheadedness from returning.
Make sure you know how you react to this medication before driving, using machinery or doing anything else that could be dangerous if you are dizzy.
Inform your doctor immediately if you become sick while taking this medication, especially if you have severe or continuous nausea, vomiting or diarrhea.
These conditions may cause you to lose too much water or salt and may lead to hypotension (low blood pressure). You can also lose water by sweating, so it is important to drink plenty of water during exercise or hot weather.
Hyperkalemia (high potassium in the blood) may occur while taking this medication.
Inform your doctor immediately if you have abdominal or stomach pain, confusion, difficulty breathing, irregular heartbeat, nausea or vomiting, nervousness, numbness or tingling in the hands, feet or lips, shortness of breath or weakness or heaviness in the legs.
Do not use supplements or salt substitutes containing potassium without first asking your doctor.
Inform any doctor or dentist who treats you that you are using this medication. You may need to stop using this medication several days before a surgery or medical condition.
Drinking alcohol or taking narcotic pain relievers or sleeping pills with this medication may intensify feelings of lightheadedness, dizziness or faintness.
Tell your doctor if you are drinking alcohol or using pain relievers or sleeping pills.
This medication may affect blood sugar levels. Inform your doctor if you notice a change in the results of your blood or urine sugar tests or if you have any questions.
Do not take any other medications without asking your doctor, including over the counter medications for appetite control, asthma, colds, cough, allergies or sinus problems, as these may increase your blood pressure.
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