1 What is Antiflex?

Brand: Antiflex, Mio-Rel, Norflex, Orfro, Orphenate

Generic: Orphenadrine

Antiflex is a skeletal muscle relaxant which acts in the central nervous system (CNS) to produce its muscle relaxant effects.

It is often used to help relax certain muscles in your body and relieve the stiffness, pain, and discomfort caused by strains, sprains, or another injury to your muscles.

However, this medicine is generally used for the treatment of painful muscle conditions along with rest and physical therapy. It may be used for other conditions as determined by your doctor.

This medicine is available in solution form only with your doctor's prescription.

2 What to Know Before Using

If you are about to start using Antiflex, speak with your doctor about what you need to know, the risk-benefit ratio of taking the drug should be considered carefully. The suitable drug therapy is chosen by a doctor with the active participation of the patient.

There are some important factors such as drug interactions, the presence of any metabolic impairment, history of hypersensitivity reaction, pregnancy, lactation etc. that may alter the desired therapeutic effects of a medicine.

Sometimes the presence of other health disorders affects the beneficial effects of this medicine and even may cause serious toxic effects.

The use of this medicine is contraindicated in certain medical conditions such as known hypersensitivity reactions, glaucoma, stomach ulcer or intestinal blockage, bladder blockage, trouble swallowing due to certain esophageal problems, enlargement of the prostate, or myasthenia gravis.

Further, you should tell your doctor if you have any other medical problems, especially if you have a history of heart problems (e.g. fast or irregular heartbeat), stomach or bowel problems (e.g. inflammation, enlarged colon), increased ocular pressure, and kidney or liver problems.

In addition, certain medicines should not be used along with this medicine. It is always recommended to consult with your doctor if you are in need of some other medications or even any over-the-counter medicine for another health problem in order to avoid unwanted toxic effects.

In addition, you should have the knowledge of following drug interactions before you start receiving this medicine:

  • Phenothiazines (e.g. chlorpromazine) should not be used concurrently because their effectiveness may be decreased by orphenadrine.
  • Propoxyphene is also avoided because confusion, anxiety, or tremors may occur.

Since this is not a complete list of all interactions that may occur, ask your doctor if orphenadrine may interact with other drugs that you take.

Studies over animal have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of this medicine in pregnant women despite potential risks.

3 Proper Usage

To use Antiflex properly, you must follow all instructions given by your doctor. The dosage schedule and the duration of drug therapy depend on the particular medical problem for which you are going to use this medicine.

The therapeutic dose may also vary with the patient’s condition or requirement and the strength of the medicine as well. This medicine is usually given to the patients by a nurse or other trained health professional at your doctor’s chamber, hospital, or clinic.

This injection is intended for intravenous or intramuscular use. If you want to use this product at home, a healthcare provider will teach you how to use.

Further, it is advised to store the medicine in a closed container at room temperature away from heat, moisture, and direct light.

All kinds of medicines should be kept out of the reach of children. However, outdated medicines should be disposed of by an appropriate way.

4 Precautions to Take

Before using Antiflex, there are some precautions you must take. Firstly, regular visits to your doctor are recommended to check the prognosis while undergoing any drug therapy.

Additionally, the following guidelines should be followed:

  • Make sure you tell your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
  • Do not use any prescription or nonprescription medicine, herbal preparation, or dietary supplement without checking with your doctor.
  • Use this drug cautiously in elderly patients because they are more sensitive to its side effects, especially confusion.
  • It is not recommended to use this medicine in children because the safety and effectiveness have not been confirmed.
  • Some laboratory tests (e.g. blood cell counts, kidney function tests, liver function tests, etc.) may be carried out to monitor your condition or check for side effects.

5 Potential Side Effects

Make sure you meet with your doctor in using Antiflex to avoid unwanted potential side effects. A headache, dizziness, lightheadedness, excitement, irritability, weakness, nervousness, restlessness, etc. are the minor side effects that may not need any medical attention.

These side effects usually go away during the treatment episode as your body adjusts to the medicine. Your healthcare professional may advise you about the ways how to prevent or reduce those unwanted side effects.

Sometimes you may need to consult with the doctor immediately if you notice any of the following toxic effects, especially:

Besides, you should know about the symptoms of overdose.

You must not delay asking for emergency help if you notice any of the following symptoms of drug overdose:

  • Blurred vision
  • Confusion
  • Delirium
  • Drowsiness
  • Dry mouth
  • Flushing of face
  • Hallucinations
  • Troubled breathing
  • Urinary retention

Other side effects not listed may also occur in some patients while taking orphenadrine. If any other effects are noticed, you should consult a healthcare professional for medical advice.