1 What is Arava?

Brand: Arava

Generic: Leflunomide

Arava is a drug which is used for the treatment of active rheumatoid arthritis. It is used to reduce signs and symptoms, inhibit structural damage as evidenced by X-ray erosions and joint space narrowing and improve physical function. This drug contains leflunomide and can be used with other drugs for rheumatoid arthritis.

Arava is available as film coated tablets containing 10 mg, 20 mg or 100 mg of leflunomide.


You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

This medication should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.


Arava may interact with medications such as:

  • Warfarin
  • Rifamycins (e.g., rifampin)
  • Drugs affecting the liver (e.g., methotrexate)
  • Cholestyramine
  • Other drugs that weaken the immune system (e.g., tacrolimus, cyclosporine)

Side Effects

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as

  • Rash
  • Itching
  • Swelling


Before taking this medication, tell your doctor or pharmacist if you have the following:

2 Related Clinical Trials