Astramorph PF

1 What is Astramorph PF?

Brand: Astramorph PF, Duramorph, Infumorph

Generic: Morphine injection

Morphine injection is a narcotic analgesic that is used to relieve pain that fails to respond to other pain medication. It works on the central nervous system to relieve pain. This medicine can also be used during preoperative or intraoperative phase.

Morphine can be addictive and may cause mental or physical dependence. However, addiction is unlikely to occur when narcotics are used to alleviate the pain. Also, withdrawal side effects may occur if you stopped using it abruptly after prolonged use. Severe withdrawal side effects can be prevented if you gradually reduce the dose you take over a period of time before totally stopping the treatment.

This product is available in solution and injectable forms.

2 What to Know Before Using

Before taking this medication, tell your healthcare professional first if you are allergic to this drug or to any other drugs.

Safety and effectiveness of this medication in infants younger than 1 month of age have not been established. It is not recommended for children to be administered a morphine injections in the back area.

Although this medicine have not demonstrated geriatric-specific problems, older patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving morphine injection.

Pregnancy category C – The use of morphine injection during pregnancy is warranted only if benefits justify risks to the fetus and only when no alternative management is appropriate.

There are no adequate studies whether morphine injection can pass through breast milk or if it could cause harmful effects to the infant. Discuss with your doctor if you are breastfeeding a baby.

Taking this medicine with Naltrexone is not recommended. Your doctor may choose not to treat you with this medication or change some of the other medicines you take.

Taking this medicine with any of the following medications is usually not recommended, but with exception in some cases. Your doctor may change the dose or the frequency of one or both of your medicines if both medicines are prescribed together.

  • Abiraterone
  • Acepromazine
  • Alfentanil
  • Alprazolam
  • Alvimopan
  • Amiodarone
  • Amisulpride
  • Amobarbital
  • Anileridine
  • Aripiprazole
  • Asenapine
  • Azithromycin
  • Baclofen
  • Benperidol
  • Brofaromine
  • Bromazepam
  • Buprenorphine
  • Buspirone
  • Butabarbital
  • Butalbital
  • Butorphanol
  • Captopril
  • Carbinoxamine
  • Carisoprodol
  • Carphenazine
  • Carvedilol
  • Chloral Hydrate
  • Chlordiazepoxide
  • Chlorpromazine
  • Chlorzoxazone
  • Cimetidine
  • Clarithromycin
  • Clobazam
  • Clonazepam
  • Clorazepate
  • Clorgyline
  • Clozapine
  • Cobicistat
  • Codeine
  • Conivaptan
  • Cyclobenzaprine
  • Cyclosporine
  • Dexmedetomidine
  • Dezocine
  • Diacetylmorphine
  • Diazepam
  • Dichloralphenazone
  • Difenoxin
  • Dihydrocodeine
  • Diltiazem
  • Diphenhydramine
  • Diphenoxylate
  • Donepezil
  • Doxorubicin
  • Doxorubicin Hydrochloride Liposome
  • Doxylamine
  • Dronedarone
  • Droperidol
  • Enflurane
  • Erythromycin
  • Estazolam
  • Eszopiclone
  • Ethchlorvynol
  • Ethopropazine
  • Ethylmorphine
  • Felodipine
  • Fentanyl
  • Flibanserin
  • Flunitrazepam
  • Fluphenazine
  • Flurazepam
  • Fluspirilene
  • Fospropofol
  • Furazolidone
  • Halazepam
  • Haloperidol
  • Halothane
  • Hexobarbital
  • Hydrocodone
  • Hydromorphone
  • Hydroxyzine
  • Iproniazid
  • Isocarboxazid
  • Isoflurane
  • Itraconazole
  • Ivacaftor
  • Ketamine
  • Ketazolam
  • Ketobemidone
  • Ketoconazole
  • Lazabemide
  • Levorphanol
  • Linezolid
  • Lomitapide
  • Lopinavir
  • Lorazepam
  • Lormetazepam
  • Loxapine
  • Meclizine
  • Medazepam
  • Melperone
  • Meperidine
  • Mephobarbital
  • Meptazinol
  • Mesoridazine
  • Metaxalone
  • Methadone
  • Methdilazine
  • Methocarbamol
  • Methohexital
  • Methotrimeprazine
  • Methylene Blue
  • Methylnaltrexone
  • Midazolam
  • Moclobemide
  • Molindone
  • Moricizine
  • Morphine
  • Morphine Sulfate Liposome
  • Nalbuphine
  • Nalmefene
  • Nalorphine
  • Naloxone
  • Nialamide
  • Nicomorphine
  • Nilotinib
  • Nitrazepam
  • Nitrous Oxide
  • Olanzapine
  • Opium
  • Opium Alkaloids
  • Orphenadrine
  • Oxazepam
  • Oxycodone
  • Oxymorphone
  • Papaveretum
  • Paregoric
  • Pargyline
  • Pentazocine
  • Pentobarbital
  • Perazine
  • Periciazine
  • Perphenazine
  • Phenelzine
  • Phenobarbital
  • Pimozide
  • Piperacetazine
  • Pipotiazine
  • Piritramide
  • Prazepam
  • Primidone
  • Procarbazine
  • Prochlorperazine
  • Promazine
  • Promethazine
  • Propofol
  • Propoxyphene
  • Quazepam
  • Quercetin
  • Quetiapine
  • Quinidine
  • Ramelteon
  • Ranolazine
  • Rasagiline
  • Remifentanil
  • Remoxipride
  • Ritonavir
  • Safinamide
  • Samidorphan
  • Secobarbital
  • Selegiline
  • Sertindole
  • Simeprevir
  • Sodium Oxybate
  • Sufentanil
  • Sulpiride
  • Sunitinib
  • Suvorexant
  • Tapentadol
  • Telaprevir
  • Temazepam
  • Thiethylperazine
  • Thiopropazate
  • Thioridazine
  • Ticagrelor
  • Tilidine
  • Tizanidine
  • Tocophersolan
  • Tolonium Chloride
  • Toloxatone
  • Topiramate
  • Tramadol
  • Tranylcypromine
  • Triazolam
  • Trifluoperazine
  • Trifluperidol
  • Triflupromazine
  • Trimeprazine
  • Verapamil
  • Zaleplon
  • Zolpidem
  • Zopiclone
  • Zotepine

Taking this medicine with any of the following medications may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. Your doctor may change the dose or the frequency of one or both of your medicines if both medicines are prescribed together.

Some medical conditions can interact with this medication.

Tell your doctor if you have any of the following conditions:

3 Proper Usage

Morphine is administered by your health care professionals through muscle or a vein. It can also be administered via needle or catheter into your back.

Small doses will be given administered until your condition improves. Your doctor will then switch you to an oral medicine that works the same way. Talk to your doctor if you have any concerns about this.

4 Precautions to Take

Check with your doctor on regular visits to monitor your progress with the medication.

This medicine will add to the effects of alcohol and other CNS depressants. Check with your doctor before taking any of those medications while you are using morphine.

Call your doctor for instructions if you feel that the medicine is not working well. Excessive use of this medication may cause physical or mental dependence.

Prolonged use of narcotics can cause severe constipation. Your doctor may recommend you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet to avoid this problem.

Slowly get up from a lying or sitting position since this medication may cause dizziness, lightheadedness, or fainting. Check with your doctor if this problem continues or gets worse.

This medicine can cause dizziness or drowsiness. Avoid driving, operating machineries, or any other risky activities when you take this medication.

Tell your doctor that you are using this medicine before undergoing any kind of surgery or emergency treatment. Serious undesirable effects can occur if certain medicines are given together with morphine.

Do not stop using this medication abruptly without checking to your doctor especially if you are using this medication for several weeks or longer. This may prevent you from having withdrawal symptoms such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.

Talk to your doctor if you are taking any other medication.

5 Potential Side Effects

If any of the following side effects occur, check with your doctor right away:

  • Troubled breathing
  • Irregular, fast or slow, or shallow breathing
  • Pale or blue lips, fingernails, or skin
  • Shortness of breath
  • Very slow breathing
  • Blurred vision
  • Convulsions
  • Decrease in frequency of urination
  • Decrease in the amount of urine
  • Difficulty in passing urine
  • Dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • Painful urination
  • Sweating
  • Unusual tiredness or weakness

Call for help immediately if any of the following symptoms of overdose occur:

Less serious side effects:

  • Absent, missed, or irregular menstrual periods
  • Anxiety
  • Confusion
  • Decreased interest in sexual intercourse
  • Delusions
  • Depersonalization
  • Difficulty having a bowel movement
  • False or unusual sense of well-being
  • Hallucinations
  • Headache
  • Inability to have or keep an erection
  • Itching skin
  • Loss in sexual ability, desire, drive, or performance
  • Menstrual changes
  • Nausea and vomiting
  • Stopping of menstrual bleeding

Not all side effects are listed above. If you notice any other effects, check with your healthcare professional.

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