Clofibrate is a lipid-lowering used to lower cholesterol and triglyceride levels in the blood. This drug may prevent the development of atherosclerosis in blood vessels.
Off-label use of this drug can be for treatment of diabetes insipidus. This drug requires a prescription
2 What to Know Before Using
Discuss with your healthcare professional about the risks and benefits of this drug. It has been reported in the World Health Organization (WHO) Study that clofibrate may increase the patient's risk of gallstones, cancer, liver disease, and pancreatitis, although it might also decrease the risk of heart attack.
Before taking this drug, the risks and benefits for your body should be discussed with your healthcare provider. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.
Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications. There are no specific data comparing the use of clofibrate in children and elderly with use in other age groups. This drug is not recommended for use in children under 2 years of age.
It still unknown whether the effects of this drug work exactly the same way they do in younger adults, or cause different side effects or problems in older people. Adverse effects have been reported in animal studies but studies in pregnant women or animals are still inadequate.
Studies have not determined any chance of infant risk when taking this drug during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.
Inform your healthcare professional if you are taking any other drugs such as Ciprofibrate, Atorvastatin, Ezetimibe, Fluvastatin, Lovastatin, Pravastatin, Simvastatin, Chlorpropamide, Colchicine, Furosemide, Rifampin, Rifapentine, or Tolazamide.
Intake of specific food or using alcohol or tobacco with magnesium is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.
Inform your healthcare provider for any other medical problems such as gallstones, stomach or intestinal ulcer, underactive thyroid, heart, kidney or liver disease.
3 Proper Usage
A personal diet low in fats, sugars, and/or cholesterol and exercise is first prescribed to control your condition before any drugs are given. Most people are able to control their condition through proper diet and exercise.
This drug is less effective if you are greatly overweight. Inform your healthcare professional if you are on a low-sodium, low-sugar, or any other special diet. This drug must be taken exactly as directed by your doctor.
To prevent any side effects, take this drug exactly as directed in the label or as prescribed by your healthcare professional. Following the proper diet and exercise given to you is the most vital part of controlling your condition and is necessary for the drug to work properly.
Take this drug with food or immediately after meals to lessen possible effects in the stomach. The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed.
The dosage of this drug you take depends on the medical problem for which you are using this drug. Adults with high cholesterol are given 1.5 to 2 grams of tablet per day, divided into two to four doses. Dose for children must be determined by your healthcare professional.
A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose. Keep this drug at room temperature, away from heat, moisture, and direct light.
Do not refrigerate. Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.
4 Precautions to Take
Your healthcare provider should closely monitor the effectiveness of this drug as well as check for unwanted effects. Cholesterol and triglyceride levels can be checked using blood tests and will be the basis if you should continue taking this drug.
Consult with your healthcare professional before you stop taking this drug as it may cause your blood fat levels to increase again. You will be recommended a special diet to help prevent the recurrence of your condition.
5 Potential Side Effects
Side effects may vary for each individual and prompt medical attention should be given if they occur. Inform you healthcare provider immediately if you experience any unusual symptoms. Some side effects may occur that usually do not need medical attention.
These side effects will eventually disappear as your body adjusts to the drug. Ask your healthcare professional about ways to prevent or reduce some of these side effects.
If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional.
If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.
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