1 What is Azactam?

Brand: Azactam

Generic: Aztreonam

Aztreonam is an antibiotic drug that is used to treat infections caused by gram-negative bacteria. It acts by inhibiting the bacterial cell wall synthesis. It is usually given in combination with other antibacterial drugs.

2 What to Know Before Using

Tell to your doctor if you are allergic to Aztreonam or to any other medications.

Studies of aztreonam in children have shown that this medication is effective in treating certain bacterial infections and that side effects in children are similar to those experienced by adults and elderlies. Children who were given high doses of this medicine have seen elevations of liver enzymes and reductions in white blood cell counts.

Pregnancy category B - No risks have been found in humans. This medication poses minimal risk to the infant when used during breastfeeding.

Some medical conditions can interact with this medication. Tell your doctor if you have any of the following conditions:

3 Proper Usage

You should take this medication as exactly as prescribed by your doctor and finish the full course of therapy. This medicine works best when there is a constant amount in the blood or urine.

  • Recommended dosage for adults and children 16 years of age and older: 
    • 1 to 2 grams injected slowly into a vein over a 20 to 60-minute period. This is repeated every 6 to 12 hours.
  • Recommended dosage for children up to 16 years of age:
    • Dosage is based on body weight and must be determined by your doctor.

4 Precautions to Take

Your doctor will be checking you regularly to monitor the effectiveness of the medication. Blood tests may be ordered for undesirable effects.

5 Potential Side Effects

If any of the following side effects occur, check with your doctor right away:

  • Black, Tarry stools
  • Blood in urine or stools
  • Burning or Itching of vagina
  • Chest pain
  • Chills
  • Confusion
  • Convulsions (seizures)
  • Cough
  • Dark urine
  • Diarrhea
  • Difficulty in breathing
  • Discharge from vagina
  • Discomfort, Inflammation, or Swelling at the injection site
  • Dizziness
  • Eye pain
  • Fever
  • Flu-like symptoms
  • General feeling of illness
  • Headache
  • Hives
  • Light gray-colored stools
  • Loss of appetite
  • Numbness of tongue
  • Pinpoint red spots on skin
  • Seeing double
  • Skin rash, redness, or itching
  • Sore throat
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness
  • Yellow skin or eyes

Less serious side effects:

  • Abdominal or Stomach cramps
  • Altered sense of taste
  • Bad breath
  • Breast tenderness
  • Burning or Prickling feeling of skin
  • Flushing
  • Increased sweating
  • Mouth ulcers
  • Muscular aches
  • Nasal congestion
  • Nausea or Vomiting
  • Ringing, Buzzing, or Noise in ear
  • Small, Non raised, Round, Purplish or Red spots on skin
  • Sneezing
  • Trouble in sleeping

Not all side effects are listed above. If you notice any other effects, check with your healthcare professionals.

6 Related Clinical Trials