1 What is Carbihist?

Brand: Carbihist, Histex PD, Palgic

Generic: Carbinoxamine Maleate

Carbinoxamine maleate is a drug which is used to treat symptoms of seasonal and perennial allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, urticaria and angioedema (mild) and dermatographism. This drug is also used to treat anaphylactic/ allergic reactions.

Carbinoxamine maleate is available in two preparations:

  • As an oral solution containing carbinoxamine maleate 4 milligrams in 5 milliliter
  • As a tablet containing carbinoxamine maleate 4 milligrams


You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

This medication should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.


Carbinoxamine maleate may interact with medications such as:

  • Antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray)
  • Antispasmodics (e.g., atropine, belladonna alkaloids)
  • Drugs for Parkinson's disease (e.g., anticholinergics such as benztropine, trihexyphenidyl)
  • MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine)
  • Scopolamine
  • Tricyclic antidepressants (e.g., amitriptyline)
  • Certain antihistamines (e.g., diphenhydramine)
  • Anti-seizure drugs (e.g., carbamazepine)
  • Medicine for sleep or anxiety (e.g., alprazolam, diazepam, zolpidem)
  • Muscle relaxants
  • Narcotic pain relievers (e.g., codeine)
  • Psychiatric medicines (e.g., chlorpromazine, risperidone, amitriptyline, trazodone)

Side Effects

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking this medication, tell your doctor or pharmacist if you have the following:

  • Allergy to carbinoxamine
  • Breathing problems (e.g., asthma, emphysema)
  • A certain eye problem (glaucoma)
  • Heart problems
  • High blood pressure
  • Liver disease
  • Seizures
  • Stomach problems (e.g., ulcers, blockage)
  • Overactive thyroid (hyperthyroidism)
  • Urination problems (e.g., trouble urinating due to enlarged prostate, urinary retention)
  • Pregnancy or lactation