Minocycline is a tetracycline antibiotic that is used for the treatment of moderate to severe acne vulgaris in patients 12 years of age and older. This drug kills bacteria by interfering with the protein synthesis of bacteria.
Also, this drug can be used for other bacterial infections of the body, anthrax infection, or for patients who are allergic to penicillin. This drug is not indicated for use against viral infections. This drug requires a prescription.
2 What to Know Before Using
Before taking this drug, the risks and benefits for your body should be discussed with your healthcare provider. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.
Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications. There are no studies reporting pediatric-specific problems that would limit the usefulness of minocycline extended-release capsules and tablets in children 12 years of age and older while safety and efficacy of this drug have not been established in children younger than 12 years of age. This drug is not recommended for use in children younger than 8 years of age as permanent discoloration of the teeth and slow bone growth have been associated effects of this drug.
Studies in the elderly have not demonstrated geriatric-specific problems that would limit the usefulness of this drug. Elderly patient may require an adjustment in the dosage of this drug since they are more likely to have kidney, liver, or heart problems.
Risks to the fetus have been determined in studies of pregnant women but the benefits of therapy may outweigh the potential risk in a life threatening situation or a serious disease. This drug may alter milk production or composition.
Monitor your infant for any side effects and adequate milk intake if an alternative to this drug is not prescribed. Discuss with your healthcare professional the potential risks and benefits before taking this drug while breastfeeding.
Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.
Inform your healthcare professional if you are taking any other drugs such as Acitretin, Amoxicillin, Ampicillin, Atazanavir, Bacampicillin, Bexarotene, Cloxacillin, Dicloxacillin, Digoxin, Etretinate, Isotretinoin, Methicillin, Nafcillin, Oxacillin, Penicillin G, Benzathine Penicillin G ,Procaine Penicillin V, Piperacillin, Pivampicillin, Sultamicillin, Temocillin, Tretinoin, Aluminum Carbonate, Basic Aluminum Hydroxide, Aluminum Phosphate, Calcium Dihydroxyaluminum, Aminoacetate Dihydroxyaluminum, Sodium Carbonate, Iron, Magaldrate, Magnesium Carbonate, Magnesium Hydroxide, Magnesium Oxide, Magnesium Trisilicate, and Vitamin A.
Intake of specific food or using alcohol or tobacco with magnesium is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco. Inform your healthcare provider for any other medical problems such as kidney or liver disease.
This drug must be taken exactly as directed by your doctor. To prevent any side effects, take this drug exactly as directed in the label or as prescribed by your healthcare professional. Long-term use of this drug is not recommended.
Take this drug with or without food and swallow this entirely with water. Do not, crush, break, or chew it. Chances of irritation or ulcers in your esophagus may be lowered when taking this drug with food. Take this drug for the full time of treatment to ensure complete therapy.
The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed. The dosage of this drug you take depends on the medical problem for which you are using this drug.
Adults with infections are prescribed with 200 milligrams of capsule followed by 100 mg every 12 hours. Some patients may start at 2 or 4 capsules of 50 mg followed by one 50 mg capsule 4 times a day. Dose in children 8 years of age and older is based on body weight and must be determined by your healthcare professional.
The initial dose is usually 4 milligram per kilogram of body weight followed by 2 mg per kg of body weight every 12 hours. The dose in children should exceed the usual adult dose. This drug is not recommended for children younger than 8 years of age.
The dose of this drug must be based on body weight and must be determined by a healthcare professional for adults and children 12 years of age and older with acne vulgaris. The dose is usually 1 milligram per kilogram of body weight per day for 12 weeks.
Use and dose in children 8 to 12 years of age must be determined by your healthcare professional. Use is not recommended to children younger than 8 years of age. A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.
4 Precautions to Take
Your healthcare provider should closely monitor the effectiveness of this drug as well as check for unwanted effects. Unwanted effects can be detected using blood and urine tests.
Consult with your healthcare professional if your symptoms do not improve or if they become worse after 12 weeks of treatment. Inform your healthcare provider if you become pregnant while you or your husband is taking this drug as this type of drug is teratogenic which can potentially harm your unborn baby or cause some birth defects.
Birth control pills may not work as well while you are using minocycline. To prevent any chances of pregnancy, use additional forms of birth control such as pills, condoms, a diaphragm, or contraceptive foam or jelly. This drug may cause darkening the color of your skin, nails, eyes, teeth, gums, or scars. This drug may cause diarrhea which may occur 2 months or more after you stop taking this drug.
Consult with your healthcare professional first before taking any anti-diarrheal medicine as this drug may make the diarrhea worse or make it last longer. Consult with your healthcare professional immediately if you have symptoms of liver problem such as pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin.
This drug may cause dizziness or light-headedness. Be careful in taking this drug before you drive, use machines, or do anything else that could be dangerous. This drug may cause increase in intracranial pressure which can lead to permanent vision loss.
Consult with your healthcare immediately if you have severe headache, blurred vision, or any vision changes, fever, rash, joint pain, or tiredness. Minocycline may cause increased sensitivity to sunlight and prolonged exposure to the sun may cause skin rash, itching, redness or other discoloration of the skin, or severe sunburn. Wear protective clothing and stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m.
Use a sunblock with SPF of at least 15 to protect your skin. Contact emergency medical services immediately if you symptoms of anaphylaxis such as very fast or irregular breathing, gasping for breath, or fainting, changes in color of the skin of the face, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and puffiness or swellings of the eyelids or around the eyes.
Inform your healthcare provider that you are taking this drug before having any medical tests as the results of some tests may be affected by this drug. Consult with your healthcare professional if you plan to have children as this drug may affect the process of sperm cell formation in males.
Consult with your healthcare professional before taking any other prescription or non-prescription drugs, and herbal or vitamin supplements.
5 Potential Side Effects
Side effects may vary for each individual and prompt medical attention should be given if they occur.
Inform you healthcare provider immediately if you experience symptoms such as black, tarry stools, blistering, peeling, or loosening of the skin, blood in the urine or stools, blurred or double vision, bulging soft spot on the head of an infant, chest pain, possibly moving to the left arm, neck, or shoulder, confusion, diarrhea, dizziness or lightheadedness, eye pain, fast heartbeat, general feeling of discomfort or illness, general tiredness and weakness, hives, itching, or skin rash joint or muscle pain large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, loss of appetite, nausea or vomiting, red skin lesions, often with a purple center severe headache severe stomach pain sores, ulcers, or white spots on the lips or in the mouth, troubled breathing, unusual bleeding or bruising, upper right abdominal or stomach pain, or yellow eyes and skin.
Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.
If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional.
If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.
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