1 What is Clinolipid?

Brand: Clinolipid, Liposyn

Generic: Fat emulsions

Fat emulsions are dietary supplements used as source of calories and essential fatty acids for patients requiring parenteral nutrition for extended periods of time and as a source of essential fatty acids for prevention of Essential Fatty Acid Deficiency (EFAD) for patients who are unable to get enough fat in their diet, usually because of certain illnesses or recent surgery. This drug requires a prescription.

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2 What to Know Before Using

Before taking this drug, the risks and benefits for your body should be discussed with your healthcare provider. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. 

Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications. ClinolipidВ® is not indicated for use in children while safety and efficacy have not been established. Studies in the elderly have not demonstrated any geriatric-specific problems that would limit the usefulness of ClinolipidВ®. 

Adverse effects have been reported in animal studies but there are inadequate studies in pregnant women or animals. Studies are still inadequate regarding infant risk when taking this drug during breastfeeding. Discuss with your healthcare professional the potential risks and benefits before taking this drug while breastfeeding. 

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects. Inform your healthcare professional if you are taking any other prescription or non-prescription drugs. 

Intake of specific food or using alcohol or tobacco with magnesium is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco. 

Inform your healthcare provider for any other medical problems such as allergy to eggs, olive oil, soybean proteins, or safflower oil, Hyperlipidemia, Lipid metabolism disorders, Blood problems, Diabetes, Gallbladder problems, Heart failure, Liver disease, Pancreatitis, Pulmonary edema, Electrolyte imbalance, Metabolic disorders, Hypertriglyceridemia, or kidney disease.

3 Proper Usage

A nurse or other trained health professional is the only one allowed to give you this drug in a hospital. This drug is given intravenously through a needle placed in one of your veins. Consult with your healthcare professional for any advice before using this drug at home. 

Follow the specific instructions given by your healthcare professional. The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed. 

The dosage of this drug you take depends on the medical problem for which you are using this drug. Adults and teenagers in need of supplementation are given based on total nutrition requirements and tolerance and must be determined by a healthcare professional. 

The starting dose is 0.5 to 1 milliliter (mL) per minute injected slowly into a vein for 15 to 30 minutes. Use in children is not recommended.

4 Precautions to Take

Your healthcare provider should closely monitor the effectiveness of this drug as well as check for unwanted effects.  

Unwanted effects can be detected using blood tests. Contact emergency medical services immediately if you experience symptoms of rapid, shallow breathing, trouble breathing, fast heartbeat, lightheadedness, dizziness, or fainting, nausea or vomiting, rash or itching skin, or a fever or chills. 

Avoid any form of contact with other people who have infections while taking this drug. Proper hand washing is recommended. Inform your healthcare professional if you have any kind of infection before you start taking this drug. 

Consult with your healthcare professional immediately if you start to have symptoms of an infection such as a cough that won't go away, weight loss, night sweats, fever, chills, or flu-like symptoms, such as a runny or stuffy nose, headache, blurred vision, or feeling generally ill. 

Consult with your healthcare professional immediately if you experience symptoms of fat overload syndrome such as fever, chills, cough, sore throat, right upper abdominal or stomach pain and fullness, or unusual bleeding, bruising, or weakness. 

This drug may also cause parenteral nutrition associated liver disease (PNALD) which usually occurs in patients who have been receiving parenteral nutrition for a long time, especially preterm infants. Check with your healthcare professional immediately if you have dark-colored urine or pale stools, nausea, vomiting, loss of appetite, pain in your upper stomach, yellow skin or eyes, redness, swelling, pain, or infection at the injection site. 

Inform your healthcare professional before having any medical tests. Consult with your healthcare professional before taking any other prescription or non-prescription drugs, and herbal or vitamin supplements.

5 Potential Side Effects

Side effects may vary for each individual and prompt medical attention should be given if they occur. 

Inform you healthcare provider immediately if you experience symptoms such as bladder pain, bloody or cloudy urine, chills, difficult, burning, or painful urination, fever, frequent urge to urinate, lower back or side pain, sore throat, vomiting, back pain, dizziness, fast heartbeat, headache, hives, shortness of breath, weakness or lightheadedness, abdominal or stomach pain, changes in skin color, changes in urination, fruit-like breath odor, increased thirst, rash, swelling and redness in the lower leg, unusual bleeding or bruising. 

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Ask your healthcare professional about ways to prevent or reduce some of these side effects. 

If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. 

If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.

6 Related Clinical Trials