Clomiphene is a selective estrogen receptor modulator of the triphenylethylene group used as a fertility medicine in some women who are unable to become pregnant. This drug causes ovulation induction to reverse anovulation or oligoovulation.
Off-label uses of this drug are treatement for male infertility, problems with corpus luteum, and problems with male sexual organs caused by pituitary or hypothalamus gland problems. This drug requires a prescription.
2 What to Know Before Using
Before taking this drug, the risks and benefits for your body should be discussed with your healthcare provider. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.
Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications. Fetal abnormalities have been reported in animals or pregnant women while taking this drug. Due to the risks of this drug, it is contraindicated in women who are or may become pregnant.
Infant risk has not been determined in studies regarding breastfeeding and intake of this drug. Discuss with your healthcare professional the possible risks and benefits before taking this drug while breastfeeding.
Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.
Inform your healthcare professional if you are taking any other prescription or non-prescription drugs. Intake of specific food or using alcohol or tobacco with magnesium is associated with an increased risk of certain side effects.
Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco. Inform your healthcare provider for any other medical problems such as unusually large ovary, ovarian cyst and endometriosis fibroid tumors of the uterus, liver disease, mental depression, or unusual vaginal bleeding.
This drug must be taken exactly as directed by your doctor. Take the correct dose every day for as many days as prescribed by your healthcare professional. The dose of this drug will be variable for different patients.
The directions on the label or the prescription by your healthcare professional should be followed. The dosage of this drug you take depends on the medical problem for which you are using this drug.
Adult women with infertility are given 50 milligrams tablets once a day for five days of a menstrual cycle. This is initially given on the fifth day of your menstrual period. You can begin taking this drug any time if you do not have menstrual cycles.
Your dose will be increased to 250 mg a day if you fail to become pregnant in the first course. Your treatment may be repeated until you do become pregnant or for up to four treatment cycles. A missed dose should be taken as soon as possible.
However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.
Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.
4 Precautions to Take
Your healthcare provider should closely monitor the effectiveness of this drug as well as check for unwanted effects. Follow the directions of your healthcare professional carefully. Ovulation is controlled by luteinizing hormone.
You are most likely to become pregnant if you have intercourse within the 24 hours after detecting the luteinizing hormone surge. Ovulation prediction test kits are used to test for this large amount of luteinizing in the urine.
Birth defects may happen if you take this drug after you become pregnant. Inform your healthcare professional if this happens. Blurred vision, difficulty in reading, or other changes in vision, dizziness or light-headedness are some side effects of this drug.
Be careful in taking this drug before you drive, use machines, or do anything else that could be dangerous. Consult with your healthcare professional if these effects are troublesome.
5 Potential Side Effects
Side effects may vary for each individual and prompt medical attention should be given if they occur.
Inform you healthcare provider immediately if you experience any unusual symptoms such as:
decreased or double vision or other vision problems
seeing flashes of light
sensitivity of eyes to light
yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects will eventually disappear as your body adjusts to the drug. Ask your healthcare professional about ways to prevent or reduce some of these side effects.
If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional.
If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional. Report any side effects to the FDA hotline at 1-800-FDA-1088.
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