Rosuvastatin is an HMG-CoA reductase inhibitor or statin that is used along with proper diet and exercise to lower triglycerides and low-density lipoproteins (bad cholesterol) in the blood. This, in turns, prevents or controls cardiovascular disease such atherosclerosis, which is characterized by the occlusion of arteries due to fatty buildup in their inner walls.
Its primary mechanism of action involves blocking HMG-CoA reductase, which is a necessary enzyme in cholesterol production.
Rosuvastatin can be purchased with a prescription.
It is usually marketed in tablet form.
2 What to Know Before Using
Discuss the pros and cons of using Rosuvastatin with your physician before starting treatment. Your doctor needs to make sure that this medication is a good fit for you.
If you’ve ever had an allergic reaction to a statin, inform your physician. He/she might use a different type of medication. Also, you should disclose, to your healthcare team, information regarding other allergies including to food, dyes, preservatives, animals, and other medications.
Studies have found that Rosuvastatin’s efficacy is not limited by any age-related factors in pediatric children ages 8 and above. The same cannot be said for those younger than 8.
Rosuvastatin is a pregnancy category X and is contraindicated in pregnant women. Its effects on a nursing baby have not been fully elucidated. Therefore, consult your physician before taking Rosuvastatin if you are breastfeeding.
Give your physician a complete list of medications you are taking. Rosuvastatin can have adverse reactions when used concomitantly with certain medications.
Using the following is normally not recommended when on Rosuvastatin treatment but can be necessary:
Using the following:
and Warfarin along with rosuvastatin can put you at risk of developing certain side effects.
Tobacco use and alcohol consumption are not advisable.
Rosuvastatin may also exacerbate other medical conditions. These include:
Follow your healthcare professional’s instructions regarding the dosage and timing of rosuvastatin. These may differ for each patient. For maximum effect, you need to take this medicine regularly. That means taking it at the same time of the day and not missing doses as much as possible.
As mentioned earlier, Rosuvastatin is used alongside with a balanced diet and exercise. Your physician will prescribe dietary changes and the type of exercises you need to do. Check with them before making any major change in diet or exercise routine.
When you are taking the tablet, swallow it whole and do not crush it. If you are on antacid therapy, take it 2 hours before rosuvastatin. Again, dosing and schedule is different for each individual and depends on the severity of your condition.
However, adults with Heterozygous familial hypercholesterolemia are prescribed 5-40 mg once a day.
Those who have Homozygous familial hypercholesterolemia and Atherosclerosis should take 20 mg daily. Take a missed dose 12 hours after or before the next schedule. Do not take 2 tablets within 12 hours.
Keep medications in a safe place at room temperature.
4 Precautions to Take
There are precautions you need to make while you are on Rosuvastatin treatment. Go to your regular checkups so your doctor can monitor your condition and prevent side effects. Your blood cholesterol and triglyceride levels need to be checked regularly as well.
Again, Rosuvastatin is contraindicated in women because it may cause harmful effects on the fetus. Avoid getting pregnant while on this medication. If you think you are pregnant, notify your physician as soon as possible.
Inform your dentist or other treating physicians that you are on this drug. Watch out for signs of rhabdomyolysis, liver damage, and myopathy.
For Rhabdomyolysis, consult your doctor if you experience dark-colored urine, muscle cramps or spasms, fever, stiffness, or unusual weakness.
In liver damage, you could have upper stomach pain, headache, vomiting, loss of appetite, dark-colored urine, general feeling of weakness, weight loss, light-colored stools, or jaundice.
Myopathy can be exhibited by unexplained muscle tenderness, pain, or weakness.
Prior to taking any OTC medication, consult your doctor first.
5 Potential Side Effects
There are several side effects associated with Rosuvastatin treatment.
Some rare side effects that need medical attention right away include:
dark-colored urine, muscle cramps, fever, muscle wasting, and unexplained weakness.
Common side effects that go away without treatment include:
body pain, congestion, sore throat, cough, hoarseness, trouble swallowing, vocal changes, and runny nose.
If you experience effects that are not listed, consult your doctor immediately.
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