1 What is Cyclogyl?

Brand: Cyclogyl, Cylate, Ocu-Pentolate

Generic: Cyclopentolate

Brand name:

US: Cyclogyl, Cylate, Ocu-Pentolate

Canada: Ak-Pentolate, Minims Cyclopentolate 05, Minims Cyclopentolate 1

Cyclopentolate is used to enlarge (dilate) the pupil. It is commonly used before eye examinations.

This medication is only available through your doctor’s prescription.

Once a medication is approved for marketing for certain uses, experience may show that it is also useful for other medical conditions.

Although these uses are not included in product labelling, this medication is used in certain patients with the following medical conditions:

This product is available in the solution form.

2 What to Know Before Using

As with all medicines, the risks must be compared to how much a medication will help you. This is a decision that you and your doctor will make together.

For this medication, there are many things that need to be considered:

Allergies: Inform your doctor if you have ever had an allergic reaction to doxorubicin or to any other medications. It is also important to inform your doctor of any non-medicine allergies such as foods, dyes, preservatives or animals.

Pediatric Usage: Infants and young children and children with blond hair or blue eyes may be particularly sensitive to the effects of cyclopentolate. This may increase the chance of side effects.

Geriatric: Elderly patients are particularly sensitive to the effects of cyclopentolate. This may increase the chance of side effects.

Pregnancy: This medication is listed as Pregnancy Category C. This means that animal studies have shown an adverse effect and no studies have been performed on pregnant women OR there are no adequate studies on pregnant animals and pregnant women.

Breastfeeding: There are no up-to-date studies in women for determining infant risk when using this medication while breastfeeding. Weigh the potential risks with the benefits before taking this medication while breastfeeding.

Drug Interactions: Certain medications should not be used together. However, in certain cases, two medications may be used together, even if an interaction might occur.

In these cases, your doctor may want to change your dose or take other precautions. When taking this medication, it is important that you inform your doctor if you are taking any of the medications listed below.

The following interactions were selected on the basis of potential significance and are not all-inclusive.

Using this medication with any of the following medication is not recommended, but may be unavoidable in some cases.

Your doctor may make the decision not to treat you with this medication or change some of the other medications you take:

  • Donepezil
  • Oxymorphone

Other Interactions: Certain medications should not be used while eating, or while eating certain foods in the case of negative interactions.

Using alcohol or tobacco with certain medications may also cause negative interactions. Talk with your doctor about the use of your medication with food, alcohol or tobacco.

Other Medical Problems: Pre-existing medical problems may affect the use of this medication.

Be sure to tell your doctor if you have any other medical problems, especially:

  • Brain damage (in children)
  • Down’s Syndrome
  • Glaucoma
  • Spastic paraylisis (in children) - May makes these conditions worse.

3 Proper Usage

Only take this medication as directed by your doctor. Do not take more, less or for a longer or shorter period of time than your doctor tells you.

To use:

Wash your hands. Tilt your head back and press your lower finger gently just beneath the lower eyelid. Pull the lower eyelid away from the eye to make a space.

Drop the medication into this space. Let go of the eyelid and close your eyes. Do not blink. Keep the eyes closed and apply pressure to the inner corner of the eye for 2-3 minutes to allow your eye to absorb the medication.

Wash your hands immediately after use to remove any medication that may be on them.

Do not touch the applicator tip to any surface. Keep the container tightly closed. This will help prevent infection of the eye.


Different patients will be given a different dose of this medication based on the strength of the medication. The number of doses you take each day, the time between doses and the length of time you take this medication depends on the reason you are taking this medication.

The following information only includes the average dose of this medication. If your dose is different, do not change it without first speaking to your doctor.

For eye examinations:

  • Adults - 1 drop 40-50 minutes before the exam. The dose may be repeated in 5-10 minutes.
  • Children - 1 drop 40-50 minutes before the exam. The dose may be repeated for 5-10 minutes.
  • Infants - 1 drop of 0.5% solution.

Missed dose: If you miss a dose of this medication, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not double dose.

Storage: Store this medication in a closed container at room temperature. Keep it away from heat, moisture, and direct light. Do not freeze.

Keep our of the reach of children. Do not keep expired medication or medication you no longer need. Ask your doctor how to dispose of any medication you do not use.

4 Precautions to Take

After you apply this medication:

Your pupils will enlarge and you will have blurred vision, especially for close objects.

Make sure your vision is clear before you drive, use machinery or do anything else that may be dangerous while you cannot see well.

You eyes will become more sensitive to light than normal. Wear sunglasses to protect your eyes from sunlight and other bright lights.

If these side effects continue longer than 36 hours after you stop using this medication, inform your doctor.

5 Potential Side Effects

Some side effects that may occur do not normally need medical attention. These may leave as your body becomes accustomed to treatment.

Ask your doctor about ways to prevent or reduce some of these side effects.

Ask your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.