1 What is Cyklokapron?

Brand: Cyklokapron

Generic: Tranexamic Acid

Brand name:


Tranexamic acid, an antifibrinolytic agent, is used to prevent or control bleeding in hemophilic patients who are undergoing dental procedures.

The effects of this medication are short term and lasts only 2 to 8 days. It works by blocking the degradation of blood clots.

Your physician can also use it for other indications as he/she sees fit. It is only available with a prescription and is sold in a solution form.

2 What to Know Before Using

As with any treatment, you need to give informed consent before using tranexamic acid. You can be informed by discussing the risks and benefits associated with this medication.

If you are allergic to tranexamic acid or similar drugs, you need to inform your physician. You also need to tell him/her if you have allergies to food, dyes, preservatives, animals, and/or other medications.

Tranexamic acid can be used in pediatric patients since its effects are not limited by any age-related factors. Dosing of tranexamic acid in geriatric patients should start at the lower end since they can be more prone to age-related heart, kidney, and liver problems.

There isn’t enough research on the effects of this medication in pregnant women. Tranexamic acid should also be used with caution in nursing mothers.

This medication should not be used with:

  • dienogest
  • desogestrel
  • drospirenone
  • estradiol cypionate
  • Ethinyl estradiol
  • estradiol valerate
  • ethynodiol diacetate
  • levonorgestrel
  • etonogestrel
  • medroxyprogesterone acetate
  • norelgestromin
  • mestranol
  • norethindrone
  • norgestimate
  • norgestrel

Your physician may change your medications or not treat you with tranexamic acid. Concomitant use of anti-Inhibitor coagulant complex, chlorpromazine or tretinoin is usually discouraged but can be necessary.

Tranexamic acid can also exacerbate the following medical conditions and should be used with caution:

  • bleeding problems
  • head injury
  • vision problems
  • blood vessel problems
  • hematuria
  • retinal artery or vein occlusion
  • seizures
  • urinary tract problems
  • disseminated intravascular coagulation
  • kidney disease

3 Proper Usage

Intravenous tranexamic acid should be administered by a physician, nurse, or trained healthcare professional. Prior to the dental procedure, 10 mg/kg should be administered.

After the procedure, 10 mg/kg should be given 3 to 4 times a day for up to 2 to 8 days or as prescribed by your doctor.

4 Precautions to Take

While on IV tranexamic acid, your physician will keep a close eye on you to make sure that the medicine is working and prevent side effects. Laboratory tests will also be required.

This medication can cause visual changes. Therefore, your doctor may instruct you to get your eyes checked by an ophthalmologist if will be receiving this medication for several days or more.

IV tranexamic acid can also increase your risk of developing thrombosis. It should not be used concomitantly with anti-inhibitor coagulant or factor IX complex concentrates.

Patients who have a history of thromboembolic diseases or have disseminated intravascular coagulation should be monitored closely.

Tranexamic acid can make you dizzy and impair your ability to drive or operate machinery. Avoid these activities while on this medication.

5 Potential Side Effects

There are a number of side effects associated with the use of IV tranexamic acid. However, not all of these can manifest.

Get medical attention right away if you experience the following:

  • diarrhea
  • depression
  • muscle twitching
  • unusually vivid dreams
  • skin rashes
  • rhythmic movement of the muscles

You also need to call your doctor or nurse as soon as possible if you have:

These symptoms, however, have rarely been reported. The incidence of convulsions, sweating, trouble seeing and unusual tiredness is not known.

Side effects that may not need medical attention include hives, itching, or redness of the skin and giddiness. You may experience other side effects not listed here. Call your doctor if this happens.

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