1 What is Cysview?

Brand: Cysview

Generic: Hexaminolevulinate (Urinary Bladder Route)

Brand name:


Hexaminolevulinate, an optical imaging agent, is used to create a better image of the bladder in a procedure called cystoscopy.

It is indicated for the improved detection of bladder cancer like non-muscle invasive tumors and carcinoma in situ.

Hexaminolevulinate should only be administered by or under the supervision of a physician.

It is usually sold as a powder for reconstitution.

2 What to Know Before Using

Before the procedure, your doctor needs to discuss the pros and cons of using hexaminolevulinate in cystoscopy. There are factors you need to consider.

You and your physician need to determine if hexaminolevulinate is right for you. Make sure you are not allergic to this imaging agent or any of its components.

You need to inform your healthcare provider if you have allergies to

  • food,
  • preservatives,
  • dyes,
  • animals,
  • other medications.

The use of hexaminolevulinate in pediatric patients has not been adequately studied. However, studies have found that the safety and efficacy of hexaminolevulinate are not influenced by any age-related factor in geriatric patients.

This imaging agent has a pregnancy category of C, which means adequate research regarding its effects in pregnant women and the fetus has not been carried out. It is also to be used with caution in nursing mothers.

How hexaminolevulinate interacts with other drugs has not been studied enough. Nonetheless, give your doctor a complete list of your medications.

Ask your healthcare provider if you need to avoid certain beverages or food before the procedure. The following medical conditions can influence the efficacy of hexaminolevulinate:

  • bladder cancer treated with Bacillus Calmette-Guerin solution in the past 3 months days,
  • hematuria,
  • porphyria (contraindicated in patients with this condition),
  • bladder pain and/or spasms.

Also, tell your nurse or doctor if you have a family history of porphyria, allergy to aminolevulinic acid, and prior exposure to Cysview.

3 Proper Usage

Hexaminolevulinate should be administered by a trained healthcare professional in either the hospital or clinic.

Normally, for adults, the recommended dose is 50 mL of the reconstituted solution. It is instilled by your nurse or physician into the bladder using a urinary catheter, which is a tube that enters your bladder.

After the imaging agent is administered, the tube is removed and the solution must stay in the bladder for a minimum of 1 hour. This means that you shouldn’t urinate within an hour of hexaminolevulinate administration.

Inform your nurse or physician if you can’t hold it in.

4 Precautions to Take

Hexaminolevulinate may cause a severe allergic reaction, which is also known as anaphylaxis.

This may be a life-threatening event and needs swift medical attention.

Your healthcare team will prepare treatments to combat this reaction.

Inform your nurse or physician immediately if you have

  • rashes,
  • hoarseness,
  • itching,
  • trouble with breathing and/or swallowing,
  • chest pain,
  • swelling of your hands, face, or mouth

after hexaminolevulinate administration,

5 Potential Side Effects

This imaging agent also has side effects. You may not actually experience all of them.

However, check in with your healthcare provider if you experience the following:

  • blood in your urine,
  • burning sensation when urinating,
  • painful urination,
  • increased urinary urgency and frequency,
  • lower stomach pain or spasm.

Those are the most commonly reported side effects of hexaminolevulinate.

The incidence for the following side effects is not known:

You can also experience side effects that are not mentioned here.

If you do, consult with your doctor as soon as possible.

6 Related Clinical Trials