1 What is Cytadren?

Brand: Cytadren

Generic: Aminoglutethimide

Brand name:


Aminoglutethimide is the drug which acts on the adrenal cortex. Production of steroids is affected by its administration. Aminoglutethimide is prescribed to treat certain tumors that affect the adrenal cortex. This drug is also used to prevent over-activity of the adrenal cortex. Moreover, Aminoglutethimide is prescribed by the health professionals to treat some other disorders.

This drug is only available with a doctor’s prescription. Patients of breast cancer, prostate cancer are given such medicine. This drug is available in tablet form in the market. You cannot get this drug without a doctor’s prescription.

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2 What to Know Before Using

If you are about to start a drug therapy, the risks and benefits ratio of taking the medicine should be considered. This is a decision that your doctor will make with your active participation.

Certain factors like present and past illness, drug interactions, metabolic impairments, hypersensitivity reactions, pregnancy, lactation etc. may alter the drug action. Thus, the use of Aminoglutethimide should be considered cautiously.

If you have had any allergic reaction to such medications or any other medicines, tell your doctor about that. Moreover, presence of other medical problems may affect the desired plasma concentration as well as the duration of action of the drug.

Make sure you tell your doctor if you have any other medical problems. Especially diabetes, heart disease, asthma, renal impairment and hepatic failure affect the needed effects of a drug. Studies and clinical trials in pregnant women have demonstrated a risk to the fetus.

But the benefits of therapy in a life threatening condition may warrant the use of drug despite potential risks.

3 Proper Usage

Medicines should be used following the directions given by a doctor. The dose of this medicine will vary according to patient’s condition or requirements. You should follow the doctor's directions and advices.

The amount of medicine that you take should not exceed the maximum therapeutic dose. Also, the frequency of your daily drug administration and the duration of drug therapy depend on the particular medical problem for which you are taking the medicine.

Therapeutic dosage of Aminoglutethimide is 4.8 mg/kg of body weight which is administered 8 hourly in an adult to treat a variety of health disorders including breast cancer and prostate cancer.

You should remain alert to take your medicine in time. If you miss any dose of this medicine, you should take it as soon as possible. But when it is time for your next dose, then skip the missed dose and go back to your regular dosing schedule.

You should store the medicine in a closed container at room temperature away from heat, moisture, and direct light. All kinds of medicines should be kept out of the reach of children. Outdated medicine must be disposed by an appropriate way.

4 Precautions to Take

Some important measures may be needed if you feel any discomfort following the drug therapy.

Firstly, you should stop using the drug and then consult with your physician immediately. Regular visits are recommended to make sure this medicine is working properly or not. Although Aminoglutethimide is well tolerated, it may cause certain unwanted adverse effects of its own.

Certain drugs (e.g. acenocoumarol, dexamethasone, digitoxin, tamoxifen, theophylline, warfarin etc.) should not be used concurrently with such medications.

It is always recommended to consult with your doctor if you are in need of some drugs for another health problem.

Sometimes it is must to avoid some particular medicines during this drug therapy in order to get rid of serious drug reactions.

5 Potential Side Effects

There are some unwanted side-effects associated with each drug that usually do not need medical attention. The side-effects usually go away during the treatment episode as your body adjusts to the medicine.

Additionally, your health care professional may advise you about the ways how to prevent or reduce those unwanted side-effects. Sometimes you may need to consult with the doctor if you feel any serious discomfort like nausea, vomiting, dizziness, drowsiness etc.

6 Related Clinical Trials