You and your doctor need to discuss the pros and cons of using oral dantrolene before beginning treatment. In order to ensure that dantrolene is appropriate for your condition, you need to consider some factors first.
You should not use this medicine if you have had allergic reactions to it or any of its ingredients. You need to tell your medical provider if you have allergies to food, animals, preservatives and other medications.
The effects of dantrolene in children younger than 5 years old have not been studies. You need to consider the risks and benefits carefully. Dantrolene should be used with caution in elderly patients.
Although there hasn’t been enough research done on the effects of dantrolene in geriatric patients, decreases in hepatic, renal, or cardiac function should be considered before initializing treatment.
Oral dantrolene is a pregnancy category C and should only be used in pregnant women if the benefits clearly outweigh the risks. Breastfeeding women should not take oral dantrolene.
Concomitant use of the following medications is usually not recommended but can be necessary at times:
You must take your oral dantrolene as directed by your physician. You can take it with or without food but do not increase the dose or the duration of treatment.
The dose and timing of oral dantrolene depend on the condition being treated. For malignant hyperthermia prevention, adults may take 25 mg once a day.
The dose may be adjusted by your healthcare provider. For muscle spasm relief, adult patients initially should take 25 mg daily. Your doctor may adjust your dose to not more than 100 mg four times daily.
The dose for children will depend on their body weight. Take a missed dose as soon as you remember. However, you should just skip it and resume normal timing if it’s almost time for the next one.
Do not double dose. Store oral dantrolene in a closed container at room temperature and away from children’s reach. Throw away expired dantrolene capsules.
4 Precautions to Take
Go to all of your follow-up appointments so that your condition can be monitored. Dantrolene can affect the liver, so the liver function must be regularly checked especially if you’re taking dantrolene on a long-term basis.
You should not get pregnant while taking dantrolene. If you suspect that you have become pregnant, tell your doctor immediately. You also need to inform your healthcare provider if you need to start new medications.
Inform your healthcare team including your pharmacist and dentist that you are currently taking dantrolene.
You should not engage in activities that need concentration like driving or operating machines while you are on dantrolene because it can cause drowsiness, weakness, and dizziness.
You should not drink alcoholic beverages while on dantrolene treatment because alcohol can increase the drowsiness effect of dantrolene.
You should also avoid taking CNS depressants like anti-anxiety medications. If you take these substances while you are on dantrolene treatment, you might experience increased CNS depression.
This medicine also makes your skin more sensitive to light. Avoid prolonged sun exposure and use a sunscreen when you go out.
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