Detrol

1 What is Detrol?

Brand: Detrol, Detrol LA

Generic: Tolterodine Tartrate

Detrol is a drug used in the treatment of overactive bladder with symptoms of urinary incontinence, urgency, and frequency. This drug is available as a tablet containing 1 mg or 2 mg of tolterodine tartrate. It is also available as extended release capsules (Detrol-LA) containing 2 mg or 4 mg of tolterodine tartrate.

Instructions:

You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

This medication should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.

Interactions:

Detrol may interact with medications such as:

  • Pramlintide
  • Anticholinergic drugs (atropine, scopolamine)
  • Other antispasmodic drugs (dicyclomine, propantheline)
  • Certain anti-Parkinson's drugs (benztropine, trihexyphenidyl)
  • Belladonna alkaloids
  • Potassium tablets or capsules
  • Drugs affecting liver enzymes that remove tolterodine from your body (such as azole antifungals including itraconazole and ketoconazole; macrolide antibiotics including clarithromycin and erythromycin; cimetidine; cyclosporine; rifamycins including rifabutin; St. John's wort; certain anti-seizure medicines including carbamazepine; vinblastine)
  • Amiodarone
  • Dofetilide
  • Pimozide
  • Procainamide
  • Quinidine
  • Sotalol
  • Macrolide antibiotics (such as erythromycin)
  • Certain antihistamines (diphenhydramine)
  • Anti-anxiety drugs (diazepam)
  • Anti-seizure drugs (phenobarbital)
  • Medicine for sleep (zolpidem)
  • Muscle relaxants
  • Narcotic pain relievers (codeine)
  • Psychiatric medicines (phenothiazines such as chlorpromazine or tricyclics such as amitriptyline)
  • Tranquilizers

Side Effects:

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling

Warnings:

Before taking this medication, tell your doctor or pharmacist if you have the following:

  • Allergy to tolterodine or to fesoterodine
  • Problems emptying your bladder (urinary retention)
  • Severe blockage of stomach or intestines (gastric retention)
  • A certain eye condition (uncontrolled narrow-angle glaucoma)
  • Other bladder problems (bladder outflow obstruction)
  • Stomach or intestinal disease (ulcerative colitis)
  • Slowed movement of stomach/intestines
  • Severe constipation
  • Controlled narrow-angle glaucoma
  • Kidney disease
  • Liver disease
  • Enlarged prostate
  • A certain muscle disease (myasthenia gravis)
  • Certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG)
  • Family history of certain heart problems (QT prolongation in the EKG, sudden cardiac death)
  • Pregnancy or lactation
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