EES 200

1 What is EES 200?

Brand: EES 200, EES 400, EES Granules, Eryc, Eryped, Eryped 200, Eryped 400, Ery-Tab, Erythrocin, Erythrocin Stearate, Ilosone, PCE, PCE Dispertab

Generic: Erythromycin

EES 200 is a broad spectrum antibiotic drug used to prevent and treat infections in many different parts of the body such as:

  • Respiratory tract infections
  • Skin infections
  • Diphtheria
  • Intestinal amebiasis
  • Acute pelvic inflammatory disease
  • Legionnaire's disease
  • Pertussis
  • Syphilis

It is also considered the best medicine in the management of recurrent attacks of rheumatic fever in patients who have shown allergic reaction to use of penicillin or sulfa drugs. Erythromycin is a macrolide antibiotics. It is effective both in killing and preventing the growth of bacteria. This medicine is available only with your doctor's prescription.

2 What to Know Before Using

Before using EES 200, you must know all about the risks and complications associated with it.

It is necessary that you inform your medical doctor of potential allergies or allergic reactions you have suffered previously to this medicines or any other.

In addition, also inform your doctor if you have any other allergies to food, dyes, or preservatives. If using nonprescription products, read the label or package ingredients carefully before using these medicines. In children, there have been no age appropriate studies for the effects of triamterene in the pediatric populations. Safety and efficacy studies have also not been performed.

Geriatric information on the relationship of age to the effect of erythromycin in geriatric patients has also not been performed. Pregnancy studies have shown an adverse effect and there are no adequate studies in pregnant women or no animal studies have been conducted and there are no adequate studies in pregnant women. There are limited studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Certain medicines may not be used together at all. However, in other cases, two different medicines may be used together even if an interaction might occur. In these cases, your doctor will make a decision on how soon and when to change the dose, or other precautions as will be necessary. Always consult your medical doctor is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. These drugs include:

  • Amifampridine
  • Astemizole
  • Bepridil
  • Cisapride
  • Colchicine
  • Dihydroergotamine
  • Dronedarone
  • Ergoloid Mesylates
  • Ergonovine
  • Ergotamine
  • Flibanserin
  • Fluconazole
  • Grepafloxacin
  • Levomethadyl
  • Lomitapide
  • Lovastatin
  • Mesoridazine
  • Methylergonovine
  • Methysergide
  • Pimozide
  • Piperaquine
  • Posaconazole
  • Saquinavir
  • Simvastatin
  • Sparfloxacin
  • Terfenadine
  • Thioridazine
  • Ziprasidone

Using these drugs with any of the following medicines is usually not recommended and may be required in most of the cases. However, when both medicines have to be prescribed together, the doctor may change the dose or frequency of use of one or both medicines for:

  • Acecainide
  • Afatinib
  • Ajmaline
  • Amiodarone
  • Amisulpride
  • Amitriptyline
  • Amoxapine
  • Anagrelide
  • Apixaban
  • Apomorphine
  • Aprepitant
  • Aprindine
  • Aripiprazole
  • Arsenic Trioxide
  • Asenapine
  • Atorvastatin
  • Azimilide
  • Azithromycin
  • Bedaquiline
  • Bosutinib
  • Bretylium
  • Brexpiprazole
  • Buserelin
  • Carbamazepine
  • Ceritinib
  • Cerivastatin
  • Chloral Hydrate
  • Chloroquine
  • Chlorpromazine
  • Cilostazol
  • Ciprofloxacin
  • Citalopram
  • Clarithromycin
  • Clindamycin
  • Clomipramine
  • Clozapine
  • Cobicistat
  • Cobimetinib
  • Crizotinib
  • Cyclobenzaprine
  • Dabrafenib
  • Darunavir
  • Dasabuvir
  • Dasatinib
  • Degarelix
  • Delamanid
  • Desipramine
  • Deslorelin
  • Dibenzepin
  • Digoxin
  • Diltiazem
  • Disopyramide
  • Dofetilide
  • Dolasetron
  • Domperidone
  • Donepezil
  • Doxepin
  • Doxorubicin
  • Doxorubicin Hydrochloride Liposome
  • Droperidol
  • Eliglustat
  • Encainide
  • Enflurane
  • Eplerenone
  • Escitalopram
  • Everolimus
  • Fentanyl
  • Fingolimod
  • Flecainide
  • Fluoxetine
  • Foscarnet
  • Gatifloxacin
  • Gemifloxacin
  • Gonadorelin
  • Goserelin
  • Granisetron
  • Halofantrine
  • Haloperidol
  • Halothane
  • Histrelin
  • Hydrocodone
  • Hydroquinidine
  • Hydroxychloroquine
  • Ibrutinib
  • Ibutilide
  • Idelalisib
  • Ifosfamide
  • Iloperidone
  • Imipramine
  • Isoflurane
  • Isradipine
  • Ivacaftor
  • Ketoconazole
  • Lapatinib
  • Leuprolide
  • Levofloxacin
  • Lidoflazine
  • Lopinavir
  • Lorcainide
  • Lumacaftor
  • Lumefantrine
  • Lurasidone
  • Mefloquine
  • Metronidazole
  • Mifepristone
  • Morphine
  • Morphine Sulfate Liposome
  • Moxifloxacin
  • Nafarelin
  • Naloxegol
  • Nilotinib
  • Nintedanib
  • Norfloxacin
  • Nortriptyline
  • Octreotide
  • Ofloxacin
  • Olaparib
  • Ondansetron
  • Oxycodone
  • Paliperidone
  • Panobinostat
  • Paritaprevir
  • Pasireotide
  • Pazopanib
  • Pentamidine
  • Perflutren Lipid Microsphere
  • Pirmenol
  • Pitavastatin
  • Pixantrone
  • Prajmaline
  • Probucol
  • Procainamide
  • Prochlorperazine
  • Promethazine
  • Propafenone
  • Protriptyline
  • Quetiapine
  • Quinidine
  • Quinine
  • Ranolazine
  • Risperidone
  • Romidepsin
  • Sematilide
  • Sertindole
  • Sevoflurane
  • Simeprevir
  • Sodium Phosphate
  • Sodium Phosphate, Dibasic
  • Sodium Phosphate, Monobasic
  • Solifenacin
  • Sonidegib
  • Sorafenib
  • Sotalol
  • Spiramycin
  • Sulfamethoxazole
  • Sultopride
  • Sunitinib
  • Tacrolimus
  • Tadalafil
  • Tedisamil
  • Telaprevir
  • Telavancin
  • Telithromycin
  • Tetrabenazine
  • Theophylline
  • Tizanidine
  • Tolvaptan
  • Topotecan
  • Toremifene
  • Trazodone
  • Trifluoperazine
  • Trimethoprim
  • Trimipramine
  • Triptorelin
  • Troleandomycin
  • Vandetanib
  • Vardenafil
  • Vasopressin
  • Vemurafenib
  • Verapamil
  • Vinblastine
  • Vincristine
  • Vincristine Sulfate Liposome
  • Vinflunine
  • Voriconazole
  • Warfarin
  • Zolmitriptan
  • Zotepine

Moreover, it is knonw that using this medicines with any of this medicines may increase the side effects of this medicines.  However, using both of the medicines may also be the best treatment for you at the same time. When both medicines have to be prescribed, the doctor will make a decuision on whether to change the dose or how often you use sone or both of the medicines. They include:

  • Alfentanil
  • Alprazolam
  • Anisindione
  • Avanafil
  • Bexarotene
  • Budesonide
  • Buspirone
  • Cyclosporine
  • Diazepam
  • Dicumarol
  • Methylprednisolone
  • Midazolam
  • Phenprocoumon
  • Roflumilast
  • Salmeterol
  • Sildenafil
  • Sirolimus
  • Tolterodine
  • Triazolam
  • Trimetrexate
  • Valproic Acid
  • Zafirlukast

It is possible for other interactions with these drugs to occur. Drugs used around or at the time of eating food may cause certain types of interactions to occur. The nature and potential of interaction are selected on the basis of potential significance and may not be all inclusive.  Other medical problems may affect the use of this medicine. It is important to inform your medical doctor if you have any other medical problem which may affect the use of this medicine.

Conditions such as bradycardia (slow heartbeat) or Heart rhythm problems (e.g., QT prolongation) or Hypokalemia (low potassium in the blood), uncorrected or Hypomagnesemia (low magnesium in the blood), when uncorrected needs to consider proper precautions when using the drugs. Often, it is not recommended to use the drugs with conditions of congestive heart failure.

The granules and tablets of the dosage forms for these medicines may contain sodium which can make this condition more worse. Elevated liver enzymes or liver disease such as cholestatic or hepatitis or myasthenia gravis which is characterized by severe muscle weakness. Use with caution since it makes this conditions worse.

3 Proper Usage

Use EES 200 as instructed by the medical doctor. One does not need to use more of the medicine or less as instructed. Moreover, you should not take it for longer duration that recommended by the doctor. This medicine needs to be used with or without the food. Measure the mixed suspension with marked measuring spoon or syringe or medicine cup. Continue using this medicine for the entire time of treatment. Even when you start to feel better after a few doses of the medicine.

The infections may not go away even after a few doses have been used and when you stop using the medicine. The dose of the medicine may be different for the different patients. Follow the orders of the medical doctor or directions provided in the label. The medicine also provides the medicine for the doses of the medicine. When your dose is different, never change the dose unless you are told by your doctor.

The medicine you use is determined by the strength of the medicine. Also, the number of doses you take every day, time allowed between the doses and the length of time you take for the medicine depends on the medical problems for which one is using the medicine. For oral dosage forms of suspensions, granules for suspensions and tablets. If using this in adults, 400 milligrams (mg) every 6 hours or 800 mg every 12 hours.

Depending on the severity of the infections, your doctor may increase the dose as needed to a maximum of about 4000 mg per day. In children, the dose is based on the body weight and must be determined by the doctor.  The dose is also usually between 30-50 milligrams (mg) per kilogram (kg) body weight, divided in equal doses and taken every 6 hours. The dose may be increased as required by your medical doctor.

In case of missed doses, the medicine needs to be taken as soon as possible. However, when almost time for the next dose, skip the missed dose and resume the regular schedule. Never double the doses. Storage of the medicine needs to be done in accordance to the recommended storage condition as described in the instructions of the medicine. Keep the medicine out of reach of children.

Never store outdated medicine that may not be needed. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep the medicine away from freezing. As for suspension drugs, keep them in the refrigerator. Throw away any unused medicine with 10 days. Store the mixed medicine for erythromycin for pediatrics suspensions at room temperature. Dispose any unused medicine within a period of 35 days after opening.

4 Precautions to Take

In using EES 200, you must be careful and take some precautions as advised by your doctor.

Regular medical checkups by the doctor are important since it helps in the monitoring of the effectiveness of the medicines. Blood and urine tests may also need to be checked for the unwanted effects. In case you or your child symptoms do not show any signs of improvement within a few days or become worse, it is necessary to check with the medical doctor for unwanted effects.

It is not advisable to use this medicine when your child is also using astemizole (Hismanal), cisapride (Propulsid), pimozide (Orap), or terfenadine (Seldane). Use of these medicines together increases the risk of more serious side effects. In addition, check with your doctor if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, unusual tiredness or weakness, or yellow eyes or skin. These may be signs of serious liver problems.

These medicines may also induce changes in the heart rhythm such as conditions called QT prolongations. This may also change the way the heart beats and cause fainting or serious side effects in some of the patients. Contact your doctor immediately if your child develops worse symptoms of heart rhythms problems such as quick pounding of the heat or uneven heart beats. Make sure your doctor knows if you are pregnant or may be pregnant before taking this medicine. Erythromycin may cause diarrhea and in some cases, it can be severe. It may also occur 2 months or more after you stop using the medicine.

Never take any medicine to treat diarrhea without first checking with your doctor. Moreover, diarrhea medicine may also make the condition worse or last longer. When having questions about this or if mild diarrhea may continue or gets worse, check with your doctor. Before going for any medical tests, inform your doctor whether you or your children have been using this medicine. The result of the tests may also be affected by the medicine.  Never take other medicines unless they have been discussed with your medical doctor. This includes prescription or non-prescription medicines, herbal or vitamin supplements.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with EES 200.

It is not common for all the side effects to occur. However, when they do occur, they will need medical attention. Check with your medical doctor if any of the following side effects occur:


  • Blistering, Peeling, or Loosening of the skin
  • Chills
  • Cough
  • Diarrhea
  • Difficulty with swallowing
  • Dizziness
  • Fast heartbeat
  • Hives or Welts
  • Joint or Muscle pain
  • Puffiness or Swelling of the eyelids or around the eyes, face, lips, or tongue red, irritated eyes
  • Red skin lesions, often with a purple center
  • Redness of the skin
  • Skin rash
  • Sore throat
  • Sores, Ulcers, or White spots in the mouth or on the lips
  • Tightness in the chest
  • Unusual tiredness or weakness
  • Wheezing

Some of the incidences are not known and they include:

  • Abdominal or Stomach cramps or tenderness
  • Bloating
  • Bloody or Cloudy urine
  • Chest pain or discomfort dark urine
  • Diarrhea, watery and severe, which may also be bloody
  • Fainting
  • Fever
  • General tiredness and weakness
  • Greatly decreased frequency of urination or amount of urine
  • Hearing loss
  • Increased thirst
  • Irregular heartbeat, recurrent
  • Irregular or slow heart rate
  • Light-colored stools
  • Nausea and vomiting pain
  • Swelling of the feet or lower legs
  • Unusual weight loss
  • Upper right abdominal or stomach pain
  • Yellow eyes and skin

Other side effects may go away naturally and therefore may not need medical attention. The side effects may go away during treatments as result of the body adjusting to the effects of the medicine. Your doctor may also advise on the best methods of preventing or reducing some of the side effects.

Check with your medical doctor if the side effects become bothersome. Ask your doctor in case of any questions about them. Sometimes, other symptoms may include:

  • Abdominal or Stomach pain diarrhea (mild)
  • Loss of appetite
  • Weight loss

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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