Edecrin Sodium

1 What is Edecrin Sodium?

Brand: Edecrin Sodium

Generic: Ethacrynate sodium injection

Edecrin Sodium is a loop diuretic or commonly referred to as a water pills. Ethacrynate sodium is given to manage fluid retention (edema) and swelling that arise from conditions of congestive heart failure, liver disease, kidney disease, and other related medical conditions. It also works on the kidneys to increase the flow of urine. This medicine is available only available with a doctor's prescription.

2 What to Know Before Using

Before Edecrin Sodium can be used, the risk of using this medicine needs to be weighed against the good will of using this medicine. This is the decision that must be reached by you and your doctor. There also several other factors that must be considered. In case of allergies, inform your medical doctors. In you have ever had unusual or allergic reactions to this medicine or any other medicines. You are also required to inform your medical doctor if you have any other form of allergies to food, dyes, preservatives or animals.

When using non-prescription products, read the label or package of the ingredients before use. Before using this medicines on the pediatrics, check on pediatric studies on the use of this medicines. Appropriate studies have not been performed on the relationship of age to the effects of Ethacrynic acid in the pediatric population. Moreover, safety and efficacy studies of the children have also not been performed.

Similarly, geriatric studies performed to date have not shown geriatric specific problems that limit the use of Ethacrynic acid in the elderly. In case of pregnancy in women, Ethacrynic acid animal studies have shown adverse effects and there are no adequate studies in pregnant women. In addition, no animal studies have been done and there are no adequate studies that have been conducted and the studies conducted to date are not adequate in pregnant women.

In breastfeeding mother, there are no adequate studies in women for determining the infant risk when using this medication while breastfeeding. It is important to weigh the significant potential for risks before using this medication while breastfeeding. As for the drug interactions, some of the medicines may not be used together completely.

In other cases, these medicines may also be used together even with the potential of a significant interactions occurring. In such like cases, the doctor may need to change the dose or other precautions as may be necessary. It is important to let know your doctor when using this medicines. The following interactions have also been selected on the basis of their potential significance and are never inclusive. Use of these medicines is often not recommended. 

However, it may be required in some cases. But when both of the medicines are required in some of the cases, both medicines may be prescribed together. The doctor may change the dose or the frequency with which you take the medicine or both medicines. Some this medicine includes:

  • Amikacin
  • Arsenic Trioxide
  • Bepridil
  • Digitoxin
  • Dofetilide
  • Droperidol
  • Foscarnet
  • Furosemide
  • Gentamicin
  • Kanamycin
  • Ketanserin
  • Levomethadyl
  • Lithium Metolazone
  • Neomycin
  • Netilmicin
  • Sotalol Streptomycin
  • Tobramycin

In addition, use of this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. They include:

  • Aceclofenac
  • Acemetacin
  • Alacepril
  • Amtolmetin Guacil
  • Aspirin
  • Benazepril
  • Bromfenac
  • Bufexamac
  • Captopril
  • Celecoxib
  • Choline Salicylate
  • Cilazapril
  • Clonixin
  • Cortisone
  • Delapril
  • Dexibuprofen
  • Dexketoprofen
  • Diclofenac
  • Diflunisal
  • Dipyrone
  • Droxicam
  • Enalapril
  • Enalaprilat
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenoprofen
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Flufenamic Acid
  • Flurbiprofen
  • Fosinopril
  • Germanium
  • Ginseng
  • Gossypol
  • Ibuprofen
  • Ibuprofen Lysine
  • Imidapril
  • Indomethacin
  • Ketoprofen
  • Ketorolac
  • Licorice
  • Lisinopril
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Meloxicam
  • Moexipril
  • Morniflumate
  • Nabumetone
  • Naproxen
  • Nepafenac
  • Niflumic Acid
  • Nimesulide
  • Oxaprozin
  • Oxyphenbutazone
  • Parecoxib
  • Pentopril
  • Perindopril
  • Phenylbutazone
  • Piketoprofen
  • Piroxicam
  • Proglumetacin
  • Propionic Acid
  • Propyphenazone
  • Proquazone
  • Quinapril
  • Ramipril
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Sodium Salicylate
  • Spirapril
  • Sulindac
  • Temocapril
  • Tenoxicam
  • Tiaprofenic Acid
  • Tolfenamic Acid
  • Tolmetin
  • Trandolapril
  • Valdecoxib
  • Zofenopril

Other interactions may occur when the medicine is used at or around times of eating food, or eating certain types of foods. Moreover, using alcohol or tobacco may cause other interactions to occur. You may also need to discuss with your healthcare professional on the use of this medicine with food, alcohol or tobacco.

Other medical problems may be present and may interfere with the use of these medicines. Inform your medical doctor if you have any other medical problems especially such as anuria or electrolyte imbalance, severe or watery diarrhea. In severe cases, one should not use these medicines in patients. In cases of diabetes, this medicine must not be used, it can caused in increase in the levels of sugar in blood.

Sometimes, it is associated with hearing problems or hypochloremia (low chloride in blood) or hypokalemia (low potassium in the blood. It also causes hypomagnesemia (low levels of magnesium) or hyponatremia (low sodium in blood) or hypovolemia (low blood volume) or liver diseases (cirrhosis), and advanced conditions of liver diseases. Use these medicines with cautions. Use of these medicines may make these conditions worse. Hypoproteinemia (low protein in the blood) may decrease the effects of the medicines in the body. In conditions of kidney diseases, or severe cases, use these medicines with caution. The effects of this medicine may be increased as a result of the slow removal of the medicines from the body.

3 Proper Usage

To use Edecrin Sodium correctly, you must follow all instructions given by your doctor.

The doctor will give you a few doses of this medicine until your medical conditions improves and you can be switched to another medicines which works in the same way. In case of any concerns, ask your medical doctor for proper professional advice.

4 Potential Side Effects

It is known that not all side effects may occur after using Edecrin Sodium. However, when it occurs, they may need medical attention. Always check with doctor for medical attention. Check on your nurse or doctor immediately when any of the following side effects occurs. Quite rare side effects include:

  • Bleeding gums
  • Bloating
  • Clay-colored stools
  • Constipation
  • Darkened urine
  • Indigestion
  • Itching
  • Large, Flat, Blue or Purplish patches in the skin
  • Loss of appetite
  • Nausea
  • Painful knees and ankles
  • Pains in stomach, side, or abdomen, possibly radiating to the back
  • Pinpoint red spots on skin raised
  • Red swellings on the skin, the buttocks, legs, or ankles
  • Skin rash
  • Unpleasant breath odor
  • Vomiting of blood
  • Yellow eyes or skin

Some of the incidences that are not yet determined include:

  • Anxiety
  • Black, Tarry stools
  • Blood in urine
  • Blurred vision
  • Cold sweats
  • Coma
  • Confusion
  • Convulsions (seizures)
  • Cool, Pale skin
  • Cough or Hoarseness
  • Depression
  • Dizziness
  • Dry mouth
  • Fast heartbeat
  • Fever with or without chills
  • Flushed, Dry skin
  • Fruit-like breath odor
  • General feeling of tiredness or weakness
  • Headache
  • Increased hunger
  • Increased thirst
  • Increased urination
  • Joint pain, stiffness, or swelling
  • Lower back, side, or stomach pain
  • Nausea
  • Nervousness
  • Nightmares
  • Painful or Difficult urination
  • Pale skin
  • Shakiness
  • Shortness of breath
  • Slurred speech
  • Sore throat
  • Sores, Ulcers, or White spots on the lips or in the mouth
  • Sweating
  • Swelling of the feet or lower legs
  • Troubled breathing
  • Unexplained weight loss
  • Unusual bleeding or bruising
  • Unusual tiredness or weakness
  • Vomiting
  • Watery and Severe diarrhea

It is important to get emergency help immediately when the following symptoms of overdose occurs:

  • Confusion
  • Decreased urination
  • Dizziness, Faintness, or Lightheadedness when getting up from a lying or sitting position suddenly
  • Increase in heart rate
  • Irregular heartbeat
  • Muscle cramps or pain
  • Numbness, Tingling, Pain, or Weakness in the hands or feet
  • Rapid breathing
  • Sunken eyes
  • Thirst
  • Trembling
  • Weakness and Heaviness of the legs
  • Wrinkled skin

Some of the side effects may occur that usually do not need medical attention. Often, these side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome. Some of the incidence that are yet to be determined include:

  • Continued ringing or buzzing or other unexplained noise in ears
  • Difficulty swallowing
  • Fear
  • Feeling of constant movement of self or surroundings
  • Feeling of fullness in the ears
  • General feeling of discomfort or illness
  • Hearing loss
  • Irritation, or pain at injection site
  • Mild diarrhea
  • Sensation of spinning stomach
  • Soreness or Discomfort
  • Weight loss

There are other side effects that are not listed here and may occur in some of the patients. In case of any other side effects, always check with your healthcare professional. Call your doctor for medical advice on the side effects. You can also report the side effects to the FDA at 1-800-FDA-1088.

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