1 What is Estrasorb?

Brand: Estrasorb

Generic: Estradiol Hemihydrate Emulsion

Estrasorb is a skin emulsion used in the treatment of moderate to severe vasomotor symptoms associated with menopause. This product contains estradiol hemihydrate 2.5 milligrams in 1 gram.


You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also use this drug at the same time each day.

This drug is to be applied to the skin only. First, wash and dry your hand before applying. The affected area should be cleansed and dried. Apply the medication to your legs, usually on the thigh and calf area as directed, usually once daily in the morning. Rub for about 3 minutes until fully absorbed. Avoid covering or wrapping the treated area. Wash your hands after use. Avoid contact with eyes, mouth or mucous membranes. If contact occurs, rinse with plenty of water.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.


Estrasorb may interact with medications such as:

  • Aromatase inhibitors such as anastrozole, exemestane or letrozole
  • Fulvestrant
  • Raloxifene
  • Tamoxifen
  • Toremifene

Side Effects

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking this medication, tell your doctor or pharmacist if you have the following: