1 What is Factrel?

Brand: Factrel

Generic: Gonadorelin (Intravenous Route, Injection Route)

Factrel is naturally released from the hypothalamus gland which causes the pituitary gland to release other sex hormones. These hormones control development in children and fertility in adults.

This drug can also be used to induce ovulation in women who do not have regular ovulation and menstrual periods due to deficiency in GnRH.

This drug requires a prescription.

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2 What to Know Before Using

Before using Factrel, the risks and benefits for your body should be discussed with your healthcare provider.

Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals.

Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications.

This drug has not been reported to cause different side effects or problems in children 12 years of age and older than it does in adults.

Use in infants is not recommended as they may be very sensitive to the effects of Gonadorelin.

There are no reports of harm to the fetus while taking this drug but studies in pregnant women or animals are still inadequate. Risks to fetuses have not been reported while taking this drug.

Infant risk is still undetermined when using this drug during breastfeeding. Discuss with your healthcare professional about potential risks and benefits of taking this drug while breastfeeding.

Drugs should not be taken together to prevent any interactions but in necessary cases inquire your healthcare provider regarding the adjustments in dosage or any other necessary precautions to prevent any unwanted side effects.

Inform your healthcare professional if you are taking any other drugs such as:

  • Androgens,
  • Estrogens
  • Progestins
  • or Glucocorticoids
  • Spironolactone
  • Levodopa
  • Oral contraceptives
  • Digoxin
  • Phenothiazines
  • Dopamine antagonists

Intake of specific food or using alcohol or tobacco with this drug is associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco.

Inform your healthcare provider for any other medical problems such as Gonadotropin-releasing hormone Adenoma, any condition that can be worsened by Estrogens, Progestins, or Androgens, such as hormone-dependent tumors.

3 Proper Usage

To use Factrel correctly, you must follow all instructions given by your doctor.

Blood samples may be taken if you are having a test done with Gonadorelin.

This drug is administered intravenously or a subcutaneously through an injection. Additional blood samples may needed to monitor the effects of the drug. Consult with your healthcare professional for the proper usage of injection pumps.

The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed. The dosage of this drug you take depends on the medical problem for which you are using this drug.

Adults with Amenorrhea or infertility caused by pituitary or hypothalamic problems are advised to inject 5 microgram into a vein or under the skin slowly over 1 minute, every ninety minutes for twenty-one days.

The dose may be decreased to 1 mcg or increased to 20 mcg if needed.

Use and dose in children up to 18 years of age must be determined by your healthcare professional.

For testing the hypothalamus and pituitary glands in adults, 0.1 milligram is injected once as a single dose under the skin or into a vein.

2 micrograms per kilogram of body weight, not to exceed a single dose of 100 mcg, must be injected once under the skin or into vein for children 12 years of age and older. Use and dose in children up to 12 years of age must be determined by healthcare professional.

4 Precautions to Take

In using Factrel, you must be careful and take some precautions as advised by your doctor.

Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness and unwanted effects of the drug.

Follow your healthcare professional’s advice if you are using Gonadorelin to help you become pregnant. Your healthcare provider can help you decide when having sexual intercourse will not result in a pregnancy with twins or triplets.

Inform your healthcare professional if you become pregnant.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Factrel.

Side effects may vary for each individual and prompt medical attention should be given if they occur.

Seek advice from your healthcare professional immediately if you experience any unusual symptoms such as:

  • Hardening of skin at place of injection
  • Hives, Itching, Pain, Redness or Swelling of skin at place of injection
  • Skin rash

Some side effects may occur that usually do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional.

Report any side effects to the FDA hotline at 1-800-FDA-1088.

6 Related Clinical Trials