Fusilev is a drug used as an antidote to the adverse effects of methotrexate, which is usually given to the patients with cancer especially bone cancer (osteosarcoma).
This drug is used as an injection to treat overdose of certain medications. Levoleucovorin acts in the body as an analogue of folic acid. This injection is also given in combination with 5FU (5 Fluorouracil) to treat and prevent the symptoms of metastatic colorectal cancer. This injection should only be given under the direct supervision of a health care expert.
Levoleucovorin is available in the following dosage forms:
Before using Fusilev, you must know all about the risks and complications associated with it. Your doctor will consider these risks before prescribing the drug and will inform you about them. Following factors should be considered before taking this drug:
Allergies: If you have had an allergic reaction to this drug in the past, inform your doctor. You should also tell your healthcare provider if you are allergic to any other drugs or food products.
Age specific problems: The data regarding the effects of this medicine specific to the pediatric age group is not yet available because appropriate studies have not been performed. The studies specific to the geriatric age group have not been carried out, that would limit the use of this drug in older age group.
Pregnancy: Regarding the safety of usage of this drug during pregnancy, it comes under “C” category, which means that relevant clinical studies show harmful effects of levoleucovorin to the developing fetus.
Drug Interactions: Certain drugs should not be used together because they can interact inside the body which can have a harmful effect. On the other hand certain drugs are allowed to be used together. So, you should tell your doctor about any other medications you are taking. If there is a chance of interaction between those two drugs, the doctor may change the dose or may prescribe an alternative drug.
Levoleucovorin should be used cautiously along with following drugs:
Furthermore, certain medications should not be taken with alcohol or tobacco, which may also result in harmful interactions. Ask your doctor about the concurrent use of this drug along with alcohol or tobacco.
You should also inform your doctor about any other medical condition you may be suffering from especially:
As with many medications, there are several potential side effects associated with Fusilev. Although these side effects may occur only in a handful of patients but if they do occur, contact your physician immediately.
This medication is associated with following side effects:
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