1 What is Fycompa?

Brand: Fycompa

Generic: Perampanel

Fycompa is used in combination with other drugs for the treatment of certain types of epilepsy like generalized tonic clonic seizures and partial seizures. It acts in the brain and decrease the neuronal activity to prevent the seizures. This medication cannot be used to cure epilepsy. It can only prevent the seizures as long as you take it.

This medicine can only be obtained on a doctor's prescription.

This product is available in the following dosage forms:

  • Tablets
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2 What to Know Before Using

Before using Fycompa, you must know all about the risks and complications associated with it. Your doctor will consider these risks before prescribing the drug and will inform you about them. Following factors should be considered before taking this drug:

  • Allergies: If you have had an allergic reaction to this drug in the past, inform your doctor. You should also tell your healthcare provider if you are allergic to any other drugs or food products.
  • Age specific problems:The data regarding the effects of this medicine specific to the pediatric age group reveals no specific adverse effect in children 12 years and older. The safety and efficacy of perampanel is not established in children less than 12 years of age. The studies specific to the geriatric age group reveal no specific side effect that would limit the safety of its usage in old age group.
  • Pregnancy: Regarding the safety of usage of this drug during pregnancy, it comes under “C” category, which means that relevant studies have revealed adverse effects on the fetus or appropriate studies have not been performed.
  • Drug Interactions: Certain drugs should not be used together because they can interact inside the body which can have a harmful effect. On the other hand certain drugs are allowed to be used together. So, you should tell your doctor about any other medications you are taking. If there is a chance of interaction between those two drugs, the doctor may change the dose or may prescribe an alternative drug.

This medication should be used with caution along with following drugs:

  • Bromazepam
  • Ceritinib
  • Buprenorphine
  • Carbamazepine
  • Clarithromycin
  • Flibanserin
  • Dabrafenib
  • Enzalutamide
  • Fosphenytoin
  • Nilotinib
  • Hydrocodone
  • Idelalisib
  • Phenytoin
  • Orlistat
  • Oxcarbazepine
  • Piperaquine
  • Rifampin
  • Rifabutin
  • Rifapentine
  • Suvorexant
  • Sodium Oxybate
  • St John's Wort

Furthermore, certain medications should not be taken with alcohol or tobacco, which may also result in harmful interactions. Ask your doctor about the concurrent use of this drug along with alcohol or tobacco.

You should also inform your doctor about any other medical condition you may be suffering from especially:
Coordination problems (eg, walking, balance)

3 Proper Usage

To avoid adverse effects, Fycompa should be used exactly as prescribed by your doctor.

Do not miss any dose. The dose of this drug varies according to the condition of each person. The number of doses per day, the time interval between the doses and the length of time you have to take the medicine depends on your condition individually and all these factors should only be determined by your healthcare provider. Follow each and every instruction of your doctor and also read the label carefully.

Do not overuse or misuse this drug and do not use it longer than the recommended time. Read all the instructions mentioned in the medication guide.

In case you miss one dose of this drug, take it as soon as you can. If it is almost time for your subsequent dose, you can then skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.


This medicine should be stored at room temperature within a closed container, away from heat, direct light and moisture. Keep this drug out of the reach of children. Do not store expired or outdated medicines or the medicine no longer needed. 

4 Precautions to Take

Before using Fycompa, there are some precautions you must take.

Perampenal can cause behavioral changes like irritability, depression, agitation and even suicidal thoughts. It can also cause dizziness, drowsiness and fainting. If you experience these effects from this medicine, drive carefully.

This medicine is also cause habit forming. Do not stop this drug suddenly; instead you should tapper off this drug gradually under the supervision of a doctor.

This medication should be used cautiously along with birth control pills and alcohol. It may not work properly when taken along with alcohol.

Regular follow-up is necessary during and after the treatment. It is important to allow your doctor to monitor your progress and to make sure that there aren’t any side effects from the medication. Contact your doctor if your symptoms have not improved even after taking the full course of treatment. The doctor may order some blood tests in order to determine the blood levels of the drug.

Avoid taking any other medicine unless thoroughly discussed with your doctor. Always ask your doctor before using any prescription, non-prescription or herbal medicine.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Fycompa. Although these side effects may occur only in a handful of patients but if they do occur, contact your physician immediately.

This medication is associated with following side effects:

  • Irritability
  • Irregular heartbeats
  • Aggression or anger
  • Clumsiness or unsteadiness
  • Anxiety
  • Dry mouth
  • Shakiness and unsteady walk
  • Hyperventilation
  • Restlessness
  • Abnormal or decreased touch sensation
  • Thoughts of killing oneself
  • Shortness of breath
  • Sleepiness or unusual drowsiness
  • Trouble sleeping
  • Changes in behavior
  • Unusual tiredness or weakness
  • Depression

Seek medical help instantly, if you experience any of these symptoms while on this medication. Also contact your healthcare professional immediately, if have overdosed on this drug.

If any of these side effects becomes more bothersome or does not go away, contact your doctor.

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