1 What is Hectorol?

Brand: Hectorol

Generic: Doxercalciferol

Hectorol is a drug used in the treatment of secondary hyperparathyroidism in patients with chronic kidney disease.

This drug is available as an oral liquid-filled capsule containing 2.5 micrograms or 0.5 microgram of Doxercalciferol. It is also available as an injection solution containing Doxercalciferol 4 micrograms in 2 milliliter.


You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

The capsule should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

The injectable form is usually given by a health care professional.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.


Hectorol may interact with medications such as:

  • Digoxin
  • Glutethimide
  • Rifampin
  • Azole antifungals including:
    • Ketoconazole
  • Macrolide antibiotics including:
    • Erythromycin
  • Anti-seizure drugs including:
    • Phenobarbital
    • or Phenytoin
  • Bile acid sequestrants such as:
    • Cholestyramine
    • or Colestipol
  • Mineral oil
  • Orlistat
  • Products that contain calcium, magnesium, phosphate, or vitamin D

Side Effects:

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking this medication, tell your doctor or pharmacist if you have the following:

  • Allergy to Doxercalciferol or to vitamin D products
  • Heart problems
  • Liver disease
  • High calcium blood levels
  • High phosphate blood levels
  • Seizure
  • Pregnancy or lactation