Before using Hemabate, you must know all about the risks and complications associated with it. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make.
For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also, tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
All Trimesters: Category C: Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine.
Make sure you tell your doctor if you have any other medical problems, especially:
Adrenal gland disease (history of)—Carboprost stimulates the body to produce steroids
Anemia—In some patients, abortion with carboprost may result in loss of blood that may require a transfusion
Epilepsy (or history of)—Rarely, seizures have occurred with use of carboprost
Fibroid tumors of the uterus
Uterus surgery (history of)—There is an increased risk of rupture of the uterus
Glaucoma—Rarely, the pressure within the eye has increased during use of carboprost
Heart or blood vessel disease (or history of)
High blood pressure (or history of)
Low blood pressure (or history of)—Carboprost may cause changes in heart function or blood pressure changes
Jaundice (history of)
Kidney disease (or history of)
Liver disease (or history of)—The body may not get carboprost out of the bloodstream at the usual rate, which may make the medicine work longer or cause toxic effects
3 Proper Usage
To use Hemabate properly, you must follow all instructions given by your doctor.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For injection dosage form:
For causing an abortion in the second trimester of pregnancy (13th to 24th week):
Adults — At first, 100 to 250 micrograms (mcg) injected deep into a muscle. Then, 250 to 500 mcg every one and one-half to three and one-half hours for up to two days.
For bleeding of the uterus after pregnancy:
Adults — 250 mcg injected deep into a muscle. Your doctor may repeat this dose every fifteen to ninety minutes as needed.
4 Potential Side Effects
As with many medications, there are several potential side effects associated with Hemabate.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Check with your doctor as soon as possible if any of the following side effects occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the side effects continue or are bothersome or if you have any questions about them.
This procedure may result in some effects, which occur after the procedure is completed, that need medical attention. Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
You may report side effects to the FDA at 1-800-FDA-1088.
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