1 What is Histatrol?

Brand: Histatrol

Generic: Histamine

Histatrol is used in various tests which can diagnose some diseases of the stomach. This test is used to determine how much acid is produced by your stomach.

How the stomach test is done

  • The stomach is emptied of its content before this test is done.
  • The calculated dose of histamine is administered under your skin.
  • Stomach contents are aspirated and then tested for acidity.

This procedure may be repeated several times. In order to prevent a possible unwanted effect, an antihistamine medicine can be given before the injection of histamine.

Histatrol can be used only under the supervision of a doctor.

This product is available in the following dosage forms:

  • Injectable
  • Solution

2 What To Know Before Using

Before using Histatrol, you must know all about the risks and complications associated with it. Your doctor will consider these risks before prescribing the drug and will inform you about them.

Following factors should be considered before taking this drug:


If you have had an allergic reaction to this drug in the past, inform your doctor. You should also tell your healthcare provider if you are allergic to any other drugs or food products.

Age-specific problems

The data regarding the effects of this medicine specific to the pediatric age group is not yet available. Its safety and efficacy have not been established in children.

The studies specific to the geriatric age group have not been carried out, therefore its safety and efficacy have not been established in older age group. However, geriatric population is more prone to having kidney, liver and heart problems.

Drug Interactions

Certain drugs should not be used together because they can interact inside the body which can have a harmful effect. On the other hand, certain drugs are allowed to be used together.

So, you should tell your doctor about any other medications you are taking. If there is a chance of interaction between those two drugs, the doctor may change the dose or may prescribe an alternative drug.

Furthermore, certain medications should not be taken with alcohol or tobacco, which may also result in harmful interactions. Ask your doctor about the concurrent use of this drug along with alcohol or tobacco.

You should also inform your doctor about any other medical condition you may be suffering from, especially:

  • High blood pressure
  • Heart disease
  • Lung disease (especially asthma)
  • Low blood pressure
  • Pheochromocytoma—Histamine may cause serious damage to the brain and blood vessels
  • Kidney disease (severe)

3 Proper Usage

Proper usage of Histatrol requires strict adherence to your doctor’s orders.

This drug is only administered in a clinical setting by a nurse or a trained healthcare professional. It is usually given through a needle placed under the skin.

4 Potential Side Effects

As with many medications, there are several potential side effects associated with Histatrol. Although these side effects may occur only in a handful of patients, but if they do occur, contact your physician immediately.

Seek medical help instantly, if you experience any of these symptoms while on this drug. Also contact your health care professional immediately, if you have overdosed on this drug. If any of these side effects becomes more bothersome or does not go away, contact your doctor.