Humulin R U-500

1 What is Humulin R U-500?

Brand: Humulin R U-500

Generic: Insulin

Humulin R U-500 is a drug which is used in the treatment of diabetic patients with marked insulin resistance (daily requirements more than 200 units). This drug is available as an injection suspension containing insulin human 500 units in 1 milliliter.


You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

This medication should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.


Humulin R U-500 may interact with medications such as:

  • Rosiglitazone
  • Other drugs for Diabetes

Side Effects

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking this medication, tell your doctor or pharmacist if you have the following:

  • Allergy to Insulin or to other types of insulins
  • Past medical history
  • Low blood sugar
  • Pregnancy or lactation

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