1 What is Hyzaar?

Brand: Hyzaar

Generic: Hydrochlorothiazide and Losartan Potassium

Hyzaar is a drug used in the treatment of hypertension. It can reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy.

This drug is available as a film coated tablet containing either of the following formulations:

  • hydrochlorothiazide 12.5 milligrams and losartan potassium 50 milligrams
  • hydrochlorothiazide 12.5 milligrams and losartan potassium 100 milligrams
  • hydrochlorothiazide 25 milligrams and losartan potassium 100 milligrams


You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

This medication should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.


Hyzaar may interact with medications such as:

  • Aliskiren
  • Lithium
  • Cholestyramine and colestipol

Side Effects

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking this medication, tell your doctor or pharmacist if you have the following:

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