1 What is Ibudone?

Brand: Ibudone, Reprexain, Vicoprofen

Generic: Hydrocodone And Ibuprofen (Oral Route)

Ibudone is used in combination to relief acute pain. They are usually used for smaller time interval, which is no longer than 10 days. This combination is not prescribed for the management of rheumatoid and osteoarthritis.

Hydrocodone belongs to a group of analgesics called narcotic analgesics. It is used to manage severe pain. It acts on the nerve receptors in the CNS to control the pain.

Hydrocodone can result in physical and mental dependence when used for a long time. Dependence is the habit-forming property of a drug. If the treatment is stopped abruptly, physical dependence can lead to withdrawal effects on the body.

Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) which is used for the relief of inflammation, swelling and pain.

This medicine is available only through a doctor's prescription.

This product is available in the following dosage forms:

  • Tablet

2 What to know before using

Before using Ibudone, you must know all about the risks and complications associated with it.

Along with its beneficial effects, every medicine also has some adverse effects. Your doctor will consider these risks before prescribing the drug and will inform you about them. Following factors should be considered before taking this drug:


If you have had an allergic reaction to this drug in the past, inform your doctor. You should also tell your healthcare provider if you are allergic to any other drugs or food products.

Age specific problems:

The data regarding the effects of this medicine specific to the pediatric age group is not yet available. Its safety and efficacy has not been established in children less than 16 years of age.

The studies specific to the geriatric age group have not been carried out, therefore its safety and efficacy have not been established in older age group. However geriatric population is more prone to having confusion, mental problems, kidney, liver and heart problems.


Regarding the safety of usage of this drug during pregnancy, it comes under “C” category, which means that clinical trials on animals have revealed harmful effects to the developing fetus or relevant studies have not been performed.

Drug Interactions:

Certain drugs should not be used together because they can interact inside the body which can have a harmful effect. On the other hand certain drugs are allowed to be used together. So, you should tell your doctor about any other medications you are taking. If there is a chance of interaction between those two drugs, the doctor may change the dose or may prescribe an alternative drug. 

For a complete list of medications that may interact with Ibudone, speak with your doctor.

Furthermore, certain medications should not be taken with alcohol or tobacco, which may also result in harmful interactions. Ask your doctor about the concurrent use of this drug along with alcohol or tobacco.

You should also inform your doctor about any other medical condition you may be suffering from, especially:

3 Proper usage

To use Ibudone properly, you must follow all instructions given by your doctor.

Take the medication at the same time each day. The dose of this drug varies according to the condition of each person. The number of doses per day, the time interval between the doses and the length of time you have to take the medicine depends on your condition individually and all these factors should only be determined by your healthcare provider. Follow each and every instruction of your doctor and also read the label carefully.

Hydrocodone has a tendency to cause dependence (habit-forming). So, it is important that you only take the recommended dose. This drug should be used exactly as prescribed by your doctor in order to avoid adverse effects. Do not overuse or misuse this drug and do not use it longer than the recommended time. Read all the instructions mentioned in the medication guide.

In case you miss one dose of this drug, take it as soon as you can. If it is almost time for your subsequent dose, you can then skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.


This medicine should be stored at room temperature within a closed container, away from heat, direct light and moisture. Keep this drug out of the reach of children. Do not store expired or outdated medicines or the medicine no longer needed.

4 Precautions to take

Before using Ibudone, there are some precautions you must take.

This medicine may increase your risk of getting heart attack or stroke, especially if you have a history of these disorders. It can also cause liver problems. It can also lead to stomach problems like bleeding and ulceration. This combination can result in allergic reactions including anaphylaxis.

Hydrocodone will enhance the effects of alcohol or any other CNS depressants like benzodiazepines. So avoid taking them concurrently. Hydrocodone can cause severe constipation, so you may have to take laxatives. It can also lead to dizziness, drowsiness and loss of attention.

The overdose of hydrocodone can also cause serious symptoms and needs urgent medical help. This medicine can cause serious types of allergic reactions including anaphylaxis. It is a serious condition and needs emergency medical attention.

Your doctor will monitor the response to this medicine and look for any side effects. Therefore, regular follow-up is necessary during and after the treatment.

Contact your doctor if your symptoms have not improved even after taking the full course of treatment.

Avoid taking any other medicine unless thoroughly discussed with your doctor. Always ask your doctor before using any prescription, non-prescription or herbal medicine.

5 Potential side effects

If you notice any side effects of Ibudone, immediately make an appointment with your doctor.

Every medicine has a propensity to cause unwanted effects along with its desired effects. Although these side effects may occur only in a handful of patients but if they do occur, contact your physician immediately.

This medication is associated with following side effects:

Symptoms of overdose:

  • cold or clammy skin
  • Blurred vision
  • difficulty hearing or ringing or buzzing in the ears
  • confusion
  • dizziness
  • headache
  • general feeling of illness
  • mood or mental changes
  • severe drowsiness
  • nausea or vomiting
  • severe stomach pain
  • slow heartbeat
  • skin rash
  • slow or troubled breathing
  • swelling of the face, fingers, feet, or lower legs
  • stiff neck or back

Seek medical help instantly, if you experience any of these symptoms while on this drug.

Also contact your healthcare professional immediately, if have overdosed on this drug. If any of these side effects becomes more bothersome or does not go away, contact your doctor.