Juxtapid lowers cholesterol levels. It works by reducing levels of low-density lipoprotein (LDL) in the bloodstream. LDL is a protein that distributes cholesterol from the liver and intestines to the bloodstream.
Up to the time of this writing, Lomitapide is only approved to treat abnormally high cholesterol levels in patients with homozygous familial hypercholesterolemia, along with low-fat diet and other lipid-lowering treatments. Homozygous familial hypercholesterolemia is a genetic condition that causes persistently high cholesterol levels.
The effectiveness of Lomitapide in lowering cholesterol in patients without homozygous familial hypercholesterolemia is not well established. The usefulness of Lomitapide in reducing risk and death due to heart disease is also not yet determined.
Lomitapide is a prescription medication.
Significant numbers of patients using Lomitapide developed elevated liver enzymes, increased fat deposits in the liver and liver toxicities during treatment. Lomitapide must be used only according to doctor’s instructions.
2 What to know before using
Before using Juxtapid, you must know all about the risks and complications associated with it.
Note that Lomitapide is only available under a program called Juxtapid REMS Program.
According to post-marketing reports, significant numbers of patients using Lomitapide experienced liver problems. Discuss this risk with your doctor before using Lomitapide.
Be aware of the symptoms of liver problems such as
Lomitapide is highly contraindicated in patients who are pregnant or breastfeeding. Lomitapide is an FDA category X drug, which means it can cause serious harm to the unborn baby when given during pregnancy. The doctor may order you to have a pregnancy test first before prescribing Lomitapide. Do not breastfeed when receiving Lomitapide.
Note that Lomitapide can make birth control pills less effective. Ask your doctor for use barrier birth control devices like diaphragms with spermicide or condom while receiving Lomitapide.
You cannot use Lomitapide if you are allergic to it. If you experienced allergies to Lomitapide before, tell it to your doctor before receiving the drug.
Tell the doctor all of your health problems before receiving Lomitapide.
You need to mention if you have the following health conditions:
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