1 What is Levo-Dromoran?

Brand: Levo-Dromoran

Generic: Levorphanol

Levo-Dromoran is used for the treating or preventing moderate or severe pain. It is an opioid medication. It is an orally active morphine-like painkiller.

It works by acting on the brain and spinal cord to decrease the feeling of pain. The patient may become dependent (addicted) on it if taken for a long period of time.

It is administered orally and only under doctor’s prescription. It is available in the form of tablet.

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2 What to Know Before Using

Your doctor will inform you of what you need to know before using Levo-Dromoran.

Before starting, your doctor should be informed about following conditions:

Allergy: Tell your doctor if you have any allergies to food, preservatives, dyes and animals or had an allergic reaction while using this drug before.

Pediatrics: Levorphanol is not recommended for use in children younger than 18 years of age.

Elderly: It should be used with caution in old people as they may have liver or kidney disease which may require dose adjustment.

Pregnancy: Levorphanol is category C drug. It has shown adverse effects on animals but not tested on humans. It is not safe during pregnancy.

Breast-feeding: It is unknown if Levorphanol is excreted in breast milk. Do not breast-feed while taking Levorphanol.

Drug Interactions: Levorphanol interacts with many drugs. It should not be used with several drugs.

Your doctor should be informed of any other medicine which you are taking as your doctor might want to change the dosage or drug.

Some of these drugs which may cause interactions are: Naltrexone, Diazepam, Fentanyl and Risperidone.

Several other conditions may reduce its effectiveness. Make sure you inform your doctor of conditions such as:

  • History of prostate problem.
  • Seizures.
  • Addison’s disease.
  • Difficult breathing, lung disease.
  • History of drug dependence especially narcotic abuse.
  • Hypothyroidism.
  • Alcohol abuse.
  • Gallbladder surgery: Should not be used in patients with these conditions.
  • Heart disease.
  • Hypotension (low blood pressure).
  • Myocardial infarction (heart attack).
  • Respiratory depression (hypoventilation or slow breathing). Use with caution. May make these conditions worse.
  • Kidney disease.
  • Liver disease. Use with caution.

3 Proper Usage

To use Levo-Dromoran properly, you must follow all instructions given by your doctor.

Levorphanol should be used according to doctor’s direction. Do not exceed the dosage. If it is taken for a long period it may cause physical and mental dependence on this drug.

Dosage: Drug dose varies among individuals. You should follow your doctor’s direction. The following information is the average dose of this drug.

For oral dosage form, for moderate to severe pain:

Adults: 2 milligrams (mg) every 6 to 8 hours as needed. However, the dose is usually not more than 6 to 8mg per day.

Missed Dose: If you miss a dose, take it as soon as you remember it. If it’s almost the time for your next dose, skip the missed dose and go back to your regular schedule.

Doubling the dose is harmful. Storage: store at room temperature. Keep it out of reach of children.

4 Precautions to Take

Before using Levo-Dromoran, there are some precautions you must take.

Levarphanol may cause drowsiness, lightheadedness. While using Levarphanol for the first time, do not perform tasks which require alertness like driving, until you don’t know how you react to the drug.

Levorphanol should not be used with alcohol. Levorphanol may cause drowsiness, tiredness or weakness. These effects may get elevated if you use it with alcohol and other CNS depressants.

The high dose or prolonged use of Levorphanol, risk of severe drowsiness, low blood pressure, and difficult breathing increases. Do not exceed the dose without consulting your doctor.

If Levorphanol is used for longer period of time or at high doses, higher doses are required to work as effectively as before. This is known as tolerance. Consult your doctor for doses.

It should not be stopped suddenly as it may cause withdrawal symptoms, which includes anxiety, diarrhea, fever, runny nose, abnormal skin sensation, nausea, vomiting, pain, shivering or tremors and trouble to sleep.

Levorphanol doses should be reduced gradually before stopping it completely.

5 Potential Side Effects

Make sure you meet with your doctor in using Levo-Dromoran to avoid unwanted potential side effects.

All medicines have side effects. Some people have no or minor side effects.

Consult with your doctor if they become worrisome:

Severe side effects, go to your doctor immediately if any of these effects occur:

  • Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue)
  • Difficulty urinating
  • Fainting
  • Fast, slow, or irregular heartbeat
  • Itching

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.