1 What is Librax?

Brand: Librax

Generic: Chlordiazepoxide hydrochloride and clidinium bromide

Librax is used to treat gastrointestinal problems such as peptic ulcers, irritable bowel syndrome, and enterocolitis.

Chlordiazepoxide is a central nervous system depressant belonging to benzodiazepine group of drugs.

Clidinium is an anticholinergic agent that reduces stomach acid and decreases bowel spasms.

This drug combination requires a prescription.

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2 What to Know Before Using

Your doctor will inform you of what you need to know before using Librax.

Before taking this drug combination, the risks and benefits for your body should be discussed with your healthcare provider. Inform your healthcare provider for any allergic reactions to these drugs or any other drugs, foods, dyes, preservatives, or animals. Carefully read the label of non-prescription drugs for any possible allergic reaction or contraindications. Studies show no correlation of age to the effects of chlordiazepoxide and clidinium combination in the pediatric population while safety and efficacy of the combination drug have not been established.

Studies on the elderly have not demonstrated geriatric-specific problems that would limit the usefulness of chlordiazepoxide and clidinium combination. With the elderly being more sensitive to the drug combination symptoms of severe drowsiness, confusion, clumsiness, or unsteadiness are more likely to occur. A lower dose may be required in the elderly to help reduce unwanted effects.

Studies about infant risk when taking this drug combination during breastfeeding show no relationship. Consult your healthcare provider about the benefits and risks of this drug combination while breastfeeding. In cases of combination therapy, your healthcare provider may adjust the dosage or suggest other precautions.

To prevent any adverse reactions, inform your healthcare professional when you are taking any of the drugs such as Alfentanil, Amobarbital, Anileridine, Bromazepam, Buprenorphine, Bupropion, Butabarbital, Butalbital, Carbinoxamine, Carisoprodol, Chloral, Hydrate, Chlorzoxazone, Codeine, Dantrolene, Donepezil, Ethchlorvynol, Fentanyl, Flibanserin, Fospropofol, Flumazenil Potassium, Hydrocodone, Hydromorphone, Ketoconazole, Lacosamide, Levorphanol, Meclizine, Meperidine, Mephenesin, Mephobarbital, Meprobamate, Metaxalone, Methadone, Methocarbamol, Methohexital, Mirtazapine, Morphine, St John’s Wort, Sulfate, Theophylline, Liposome, Oxycodone, Oxymorphone, Pentobarbital, Phenobarbital, Primidone, Propofol, Propoxyphene, Remifentanil, Secobarbital, Sodium Oxybate, Sufentanil, Suvorexant, Tapentadol, Thiopental, and Zolpidem.

Intake of specific food or using alcohol or tobacco with this drug combination associated with an increased risk of certain side effects. Your healthcare professional can give you special instructions about the use of food, alcohol, or tobacco. Inform your healthcare of any other medical problems that may be worsened by this drug combination, especially drug or alcohol abuse or dependence or mental illness, or weakened physical condition. This drug combination should not be given to individuals with enlarged prostate or Glaucoma or Urinary bladder neck blockage. Effects of this drug combination are prolonged for patients with renal or hepatic diseases which associated with slower excretion.

3 Proper Usage

To use Librax properly, you must follow all instructions given by your doctor.

This drug must be taken exactly as prescribed by your doctor. Additional or prolonged doses could increase the chance of side effects. This drug must be taken before meals and at bedtime.

The dose of this drug will be variable for different patients. The directions on the label or the prescription by your healthcare professional should be followed.

The dosage of this drug you take depends on the medical problem for which you are using this drug.

The treatment of peptic ulcer, IBS, or enterocolitis in adults is usually prescribed with oral dosage form (capsules) of two capsules taken three or four times a day.Two capsules per day are given to older adults.

The dosage is subject to adjustment by your healthcare provider. Your healthcare provider will suggest the dosage for children with gastrointestinal problems. A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next dose.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing. Keep out of the reach of children. Dispose any outdated or expired drugs and ask your healthcare professional for the proper disposal of the drugs.

4 Precautions to Take

Before using Librax, there are some precautions you must take.

Regular visits should be made to your healthcare provider to track your progress and to monitor the effectiveness of the drug. Unwanted effects can be screened using blood tests.

Serious unwanted effects in newborns are expected when this drug is taken during pregnancy. If you think you are pregnant or if you plan to become pregnant while taking this drug, consult with your healthcare provider immediately.

Some effects specific to the elderly can be drowsiness, dizziness, light-headedness, clumsiness or being less alert than normally. Care should be taken when taking this drug before doing anything potentially dangerous.

This drug combination potentiates the effects of alcohol and other CNS depressants such as antihistamines or medicine for hay fever, other allergies, or colds, sedatives, tranquilizers, or sleeping medicine, prescription pain medicine or narcotics, barbiturates, medicine for seizures, muscle relaxants, or anesthetics, including some dental anesthetics. Consult with your healthcare professional before taking any of the aforementioned while taking the drug combination.

If you experience signs of a serious liver problem such as dark-colored urine or pale stools, nausea, vomiting, loss of appetite, or pain in your upper stomach, or yellowing of the skin or eyes, consult with your healthcare provider immediately.

If you experience signs of agranulocytosis such as unusual bleeding or bruising or weakness, consult with your healthcare provider immediately. Consult with your healthcare provider immediately if you develop any unusual and strange thoughts or behavior while you are taking chlordiazepoxide.

Confusion, worsening of depression, suicidal thoughts, and unusual excitement, nervousness, or irritability are unusual and extreme symptoms. You should consult your healthcare provider before you stop taking this drug. Your healthcare provider may slowly taper the drug before stopping it completely to reduce the possibility of withdrawal symptoms, such as convulsions (seizures), stomach or muscle cramps, tremors, or unusual behavior.

Do not take other prescription or non-prescription drugs, herbal or vitamin supplements unless they have been discussed with your healthcare provider.

5 Potential Side Effects

Make sure you meet with your doctor in using Librax to avoid unwanted potential side effects.

Side effects may vary for each individual and prompt medical attention should be given if they occur.

Abdominal or stomach pain, chills, clay-colored stools confusion, cough or hoarseness, dark urine, difficulty with speaking, dizziness, drooling, drowsiness, fever with or without chills, general feeling of tiredness or weakness, headache, itching, loss of appetite, loss of balance control, lower back or side pain, muscle trembling, jerking or stiffness, nausea, painful or difficult urination, pale skin, rash, restlessness, shakiness and unsteady walk, shuffling, walk sore, throat sores, ulcers, or white spots on the lips or in the mouth, stiffness of the limbs, swelling twisting movements of the body uncontrolled movements, especially of the face, neck, and back unpleasant breath odor, unsteadiness, trembling, or other problems with muscle control or coordination, unusual bruising or bleeding, unusual tiredness or weakness, vomiting of blood yellow eyes or skin still have unknown incidence.

If symptoms of overdose such as blurred vision change in consciousness, difficulty having a bowel movement, dry mouth, lack of coordination, loss of consciousness, sleepiness, or unusual drowsiness occur, contact emergency medical services immediately. As your body adjusts to the medicine, the side effects will slowly disappear. Ask your healthcare professional about ways to prevent or reduce some of these side effects. If any of the following side effects persists, or are inconvenient, or if you notice any other effects, or if you have any questions about them, consult with your health care professional.

Inability to have or keep an erection increase or loss in sexual ability, desire, drive, or performance, increased or decreased interest in sexual intercourse, menstrual changes, skin and blisters have been reported but have unknown incidence.

Report any side effects to the FDA hotline at 1-800-FDA-1088.

6 Related Clinical Trials