1 What is Lioresal?

Brand: Lioresal, Kemstro

Generic: Baclofen

LioresalĀ is an oral drug used for the relief of spasticity due to multiple sclerosis. It helps ease of flexor spasms and concomitant pain, clonus, and muscular rigidity. This drug may also be used in spinal cord injuries and other spinal cord diseases.

Baclofen is available as a 10-mg or as a 20 mg tablet.


You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

This medication should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day. The usual dose is 3 times a day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.


Baclofen may interact with medications/ substances such as:

  • Alcohol
  • Antihistamines (such as cetirizine, diphenhydramine)
  • Drugs for sleep or anxiety (such as alprazolam, diazepam, zolpidem)
  • Other muscle relaxants
  • Narcotic pain relievers (such as codeine)

Side Effects

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking this medication, tell your doctor or pharmacist if you have the following:

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