1 What is Lorzone?

Brand: Lorzone, Parafon Forte DSC, Remular-S,Paraflex, Relaxazone

Generic: Chlorzoxazone

Lorzone is a skeletal muscle relaxant used to relieve discomfort caused by acute painful muscle or bone conditions.

This drug acts on the spinal cord and subcortical areas of the brain to relax the muscles, thereby limiting and inhibiting any discomfort you may experience as a result of backaches or acute bone conditions such as osteoporosis.

Chlorzoxazone is a prescription drug and cannot replace rest, exercise, physical therapy, or other treatments.

2 What to know before using

Inform your healthcare professional if you are taking any other drugs, such as:

  • Alfentanil
  • Alprazolam
  • Amobarbital
  • Anileridine
  • Aprobarbital
  • Bromazepam
  • Buprenorphine
  • Butabarbital
  • Butalbital
  • Carisoprodol
  • Chloral Hydrate
  • Chlordiazepoxide
  • Chlorzoxazone
  • Clobazam
  • Clonazepam
  • Clorazepate
  • Codeine
  • Dantrolene
  • Diazepam
  • Estazolam
  • Ethchlorvynol
  • Fentanyl
  • Flibanserin
  • Flunitrazepam
  • Flurazepam
  • Halazepam
  • Hydrocodone
  • Hydromorphone
  • Ketazolam
  • Levorphanol
  • Lorazepam
  • Lormetazepam
  • Medazepam
  • Meperidine
  • Mephenesin
  • Mephobarbital
  • Meprobamate
  • Metaxalone
  • Methadone
  • Methocarbamol
  • Methohexital
  • Midazolam
  • Morphine
  • Morphine Sulfate
  • Liposome
  • Nitrazepam
  • Oxazepam
  • Oxycodone
  • Pentobarbital
  • Prazepam
  • Primidone
  • Propoxyphene
  • Quazepam
  • Remifentanil
  • Secobarbital
  • Sodium Oxybate
  • Sufentanil
  • Suvorexant
  • Tapentadol
  • Temazepam
  • Thiopental
  • Triazolam

Ingesting specific foods or using alcohol or tobacco with chlorzoxazone is associated with an increased risk of certain side effects. This is why you need to be completely upfront and honest with your physician regarding your medical history and habits such as smoking and drinking.

Your doctor can give you special instructions about the use of food, alcohol, or tobacco while taking Lorzone. Inform them of any other medical problems, especially liver disease, which may increase the risk of serious side effects. Your healthcare provider may run additional tests to determine the viability of using this drug with a weakened liver. A frank discussion should go a long way towards enabling you to ingest this drug safely.

3 Proper usage

To use Lorzone properly, you must follow all instructions given by your doctor.

The dose of this drug will vary for different patients. The directions on the label or prescription by your healthcare professional should be followed exactly. Should you miss a dose, you do not up the dosage the next time you take the medication, but rather maintain taking the dosage as prescribed at the right time.

The dosage you take depends on the medical problem being treated.

An oral dosage form (tablets) is usually prescribed for relaxing muscles in adults, with 500 milligrams taken three to four times a day. This should enable you to experience less pain and discomfort.

Use and dosage in children must be determined by your healthcare professional. If your child is being prescribed this medication, take care with the dosage and make sure they are given the right amount at the right time each day.
A missed dose should be taken as soon as possible. However, skip the missed dose and go back to your regular dosing schedule if it is almost time for your next one.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light, and do not freeze. Keep out of reach of children. Dispose of any outdated or expired drugs and ask your healthcare professional for the proper method of disposal. Make sure you peruse the label for the expiration date and throw out any remaining tablets past that date.

4 Precautions to take

Before using Lorzone, you must take some precautions. Make sure to visit your doctor regularly so they can better monitor your condition and the efficacy of the drug as it relates to your pain and discomfort.

Regular visits should be made to your healthcare provider to track your progress and monitor the effectiveness of the drug as well as check for unwanted side effects. Liver problems are associated with this drug, so it is critical you visit your doctor often to ensure your liver continues to remain healthy and is not affected as a result of ingesting Lorzone.

Stop taking this drug and consult your healthcare professional immediately if you experience symptoms such as:

  • Abdominal pain or tenderness: If you are experiencing mild to severe abdominal pain as well as tenderness around the same area while taking this drug, you need to stop right away. Consult your healthcare professional as to why you are developing these pains and seek alternative medication.
  • Clay-colored stools: If your stool turns the color of clay when voiding your bowels, this could be a result of taking Lorzone. Contact your healthcare professional to seek alternative medication.
  • Dark urine: Your urine can turn dark for various reasons, but if it is extremely dark, it could be a result of you ingesting this medication. Meet with your healthcare provider and raise the issue so they can suggest something else to help your pain and discomfort.
  • Decreased appetite: If you find your appetite has decreased since starting this medication, you need to bring this to the attention of your doctor. They may run additional tests and, if required, ask you to stop taking the drug and try out an alternative one instead.
  • Fever and headache: If you experience pain and headaches after ingesting this medicine, you may need to stop; it could be your body manifesting an allergic reaction, so consult your healthcare professional to run a few tests and, if that’s the case, suggest viable alternatives.
  • Itching: If you have persistent itching that began right after you started ingesting Lorzone, it could be a sign of an allergic reaction. Consult your healthcare professional right away so they can either prescribe a viable alternative or suggest additional medications to offset the itching.
  • Nausea and vomiting: If you are experiencing both nausea and vomiting as a result of this drug, it is time you stopped taking it and saw your doctor.
  • Skin rash: Skin rash on ingesting this drug could be your body developing an allergic reaction. Stop taking the drug right away and bring this to the attention of your doctor.
  • Swelling of the feet or lower legs: If you have swelling in the legs and feet after you started ingesting this drug regularly, chances are your body is reacting negatively to it. You need to stop taking it and bring this to the attention of your doctor right away.
  • Unusual tiredness or weakness: If you experience extreme tiredness and fatigue on taking this drug, it could be one of the side effects of Lorzone. Bring this to the attention of your doctor and get it sorted out immediately.
  • Yellow eyes or skin: If your skin and eyes have changed color and taken on a yellow hue, tell your doctor so they can attend to it right away.

Chlorzoxazone may potentiate the effects of alcohol and other CNS depressants such as antihistamines or medicine for:

  • Hay fever
  • Allergies
  • Colds
  • Sedatives
  • Tranquilizers or sleeping medicine
  • Prescription pain medicine or narcotics
  • Barbiturates
  • Seizures
  • Anesthetics, including some dental anesthetics

Consult your healthcare professional before taking any of these drugs while you are taking chlorzoxazone.

5 Potential side effects of lorzone

As with most medications, there are several potential side effects associated with Lorzone.

Side effects may vary for each individual, and prompt medical attention should be sought if they occur. You need to make a note of all side effects you experience as a result of this drug and bring them to the attention of your healthcare provider so they can look into it. Some of the side effects you may experience are listed below.

Rare symptoms include bloody or black, tarry stools, clay-colored stools, constipation, cough, dark urine, decreased appetite, difficulty swallowing, dizziness, fast heartbeat, fever, headache, hives, itching, large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, loss of appetite, nausea and vomiting, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, severe stomach pain, shortness of breath, skin rash, swelling of the feet or lower legs, tightness in the chest, unusual tiredness or weakness, vomiting of blood or material that looks like coffee grounds, wheezing, and yellow eyes or skin.

Contact emergency medical services immediately if you experience symptoms of an overdose such as:

  • Diarrhea
  • Difficult or troubled breathing
  • Drowsiness
  • General feeling of discomfort or illness with irregular headaches
  • Fast or slow, or shallow breathing and light-headedness
  • Nausea
  • Pale or blue lips, fingernails, or skin
  • Sluggishness and vomiting

Some side effects may occur that do not need medical attention. As your body adjusts to the medicine, the side effects will slowly disappear.

Ask your healthcare professional about ways to prevent or reduce some of these side effects.

If any side effects persist or you notice any others, or if you have any questions about them, consult your healthcare professional.

Bruising, large, flat, blue or purplish patches in the skin or small, red or purple spots on the skin have also been reported.

Report any side effects to the FDA hotline at 1-800-FDA-1088.