Lumizyme injection is an enzyme that treats infantile-onset Pompe disease, which is also called glycogen storage disease type II.
Alglucosidase alfa contains a human enzyme called acid alpha-glucosidase. This enzyme helps with the digestion and absorption of glycogen.
People with Pompe disease are not able to make enough of this enzyme.
This medication is only available with your doctor’s prescription.
This medication is available in the following forms:
Powder for Solution
2 What to Know Before Using
Before using Lumizyme, you must know all about the risks and complications associated with it.
As with all medicines, the risks must be compared to how much a medication will help you. This is a decision that you and your doctor will make together. For this medication, there are many things that need to be considered:
Inform your doctor if you have ever had an allergic reaction to doxorubicin or to any other medications. It is also important to inform your doctor of any non-medicine allergies such as foods, dyes, preservatives or animals.
Up-to-date Pediatric Appropriate studies have not indicated any problems that would limit the use of this medication.
No appropriate studies have been performed on the relationship of age to the effects of this medication in the elderly. Safety and efficacy have not been established.
This medication is listed as Pregnancy Category C. This means that animal studies have shown an adverse effect and no studies have been performed on pregnant women OR there are no adequate studies on pregnant animals and pregnant women.
There are no up-to-date studies in women for determining infant risk when using this medication while breastfeeding. Weigh the potential risks with the benefits before taking this medication while breastfeeding.
Certain medications should not be used together. However, in certain cases, two medications may be used together, even if an interaction might occur. In these cases, your doctor may want to change your dose or take other precautions. When taking this medication, it is important that you inform your doctor if you are taking any prescription or over the counter medications.
Certain medications should not be used while eating, or while eating certain foods in case of negative interactions. Using alcohol or tobacco with certain mediations may also cause negative interactions. Talk with your doctor about the use of your medication with food, alcohol or tobacco.
Other Medical Problems
Pre-existing medical problems may affect the use of this medication. Be sure to tell your doctor if you have any other medical problems, especially:
Cardiac hypertrophy (heart is larger than normal)
Hearth rhythm problems
Lung disease - Use with caution. May make these conditions worse.
3 Proper Usage
To use Lumizyme properly, you must follow all instructions given by your doctor.
A nurse or other trained health professional will give you this medication in a hospital. This medication is given through a needle placed in one of your veins (intravenously)
This medication must be given slowly, so the catheter will remain in place for a few hours. You may also receive other medications to help prevent possible allergic reactions to the injection.
4 Precautions to Take
Before using Lumizyme, there are some precautions you must take.
Only take this medication as directed by your doctor. Do not take more, less or for a longer or shorter period of time than your doctor tells you. Blood tests may be needed to check for unwanted effects.
Some side effects that may occur do not normally need medical attention. These may leave as your body becomes accustomed to treatment. Ask your doctor about ways to prevent or reduce some of these side effects.
Talk to your doctor if any of the following side effects continue or are bothersome, or if you have questions:
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