1 What is Metastron?

Brand: Metastron

Generic: Strontium Chloride Sr 89

Metastron is an artificial radioisotope. It is used in the treatment of metastatic bone cancer (cancer which has spread from different organs to bones).

It helps in relieving bone pain which is caused by different types of cancers as it allows for targeted radiations to metastatic lesions, inducing killing of cancerous cells and membrane and so provide relief from pain.

It may also be used to diagnose some diseases. It is given by or under your doctor’s supervision and is available in solution and injectable form.

2 What to Know Before Using

Before using Metastron, you must know all about the risks and complications associated with it.


Inform your doctor if you are allergic to any food, preservatives, dyes, or had an allergic reaction when you used this drug before.


There are no adequate studies done which prove Strontium Chloride Sr 89’s effects in children. Use it after consulting your doctor. However, safety and efficacy have not been established.


This medicine does not cause any different side effects or problem than it does in younger adults.


It is a category D drug. It should not be used in pregnancy. It can cause abnormalities or death of an unborn baby.

Breast Feeding

There are no adequate studies which prove that Strontium Chloride Sr 89 passes into breast milk. It is better to stop nursing while having this treatment. If you are using Strontium Chloride Sr 89 while nursing, discuss it with your doctor for possible risk factors.

Drug Interactions

Strontium Chloride Sr 89 may interact with other drugs. Your doctor should be informed of any other medicines which you are taking. He/she may want to change the dosage or drug.

Other Medical Conditions

Several other conditions may reduce its effectiveness. Make sure you inform your doctor of any other conditions which you have.

3 Proper Usage

To use Metastron properly, you must follow all instructions given by your doctor. If you do not understand them, ask your doctor in advance.

One should inform their doctor if they have difficulty in controlling their bladder (urine incontinence).

In such situation, your doctor may want to take precautions to prevent contamination of clothing, bed linen, and the environment.


It is different for different patients. Follow your doctor instructions.

4 Precautions to Take

Before using Metastron, there are some precautions you must take. Your doctor should check your daily progress at regular visits.

He/she may want a blood or urine test to check for unwanted effects. Strontium Chloride is excreted in urine and feces.

To prevent contamination of your home, you should:

  • flush twice after using the toilet
  • wash any spilled urine with a tissue and flush that tissue away
  • wash your hands after using the toilet
  • wash your clothes and bed linens immediately if they become contaminated with your urine or blood
  • Wash them separately from other clothes and if you cut yourself
  • wash away any spilled blood

It is a bone marrow suppressant. It temporarily reduces your white blood cells and platelets, and so making you susceptible to infections and bleeding. While using this drug you should avoid people with the infection.

Inform your doctor immediately if you notice:

Be careful when using a regular toothbrush, dental floss, or toothpick. Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.

5 Potential Side Effects

As with many medications, there are several potential side effects associated with Metastron. Some people may experience none or minor side effects.

Consult with your doctor if they become problematic or frequent:

Rare side effects are:

  • Fatal septicemia following leukopenia
  • Bone marrow toxicity
  • Chills and fever

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

6 Related Clinical Trials