Mozobil

1 What is Mozobil?

Brand: Mozobil

Generic: Plerixafor

Mozobil is a prescription drug, which is used in treating multiple myelomas (MM) and non-Hodgkin’s lymphoma (NHL).

This drug is used together with G-CSF or granulocyte-colony stimulating factors, such as filgrastim or pegfilgrastim in mobilizing HSC or hematopoietic stem cells for collection and transplantation. 

2 What to Know Before Using

Before using Mozobil, you must know all about the risks and complications associated with it. The risks and benefits the medicine offer must be weighed.

For this medicine, you and your doctor must consider the following:

Allergies

If you have any unusual reaction to any medicine, be sure to tell your doctor about it. Additionally, disclose other types of allergies - foods, preservatives, animals, or dyes, if there are any. Read the package ingredients carefully and make sure you are not allergic to any of its ingredients.

Pediatric

Appropriate studies are done and have not shown pediatric-specific problems limiting the usefulness of this drug in children.

Geriatric

Most recent appropriate studies have not shown geriatric-specific problems that would limit the effects of plerixafor in the elderly. It is important, however, to use this medicine with utmost care with older people, since they are more prone to age-related kidney problems that may need dosage adjustment.

Pregnancy

According to studies, using this drug is risky to the fetus. Nevertheless, the benefits of taking this drug may outweigh the risks, especially in life-threatening situations.

Breastfeeding

Although there are no adequate studies in lactating mothers that determine potential risk in infant when breastfeeding, the potential benefits should be weighed against the risks before taking this medication.

Drug Interactions

Certain medicines have adverse effects when used together. Nevertheless, it is still possible to take other medicines when using this drug. Make sure to inform your doctor about other drugs you are taking, so that alterations and precautions will be made if necessary. Inform your doctor about any other medications you are taking, including prescription and nonprescription drugs, vitamins, and herbal supplements.

Other medical problems

If you have other medical problems, how you use this drug may be affected. Talk to your doctor about your other medical problems, if there are any, especially, cancer of the bone marrow or other conditions of the bone marrow, leukocytosis, enlarged spleen, thrombocytopenia, and kidney disease.

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3 Proper Usage

To use Mozobil properly, you must follow all instructions given by your doctor. Mozobil is given through injection under the skin. It must only be administered by a trained health professional.

4 Precautions to Take

Before using Mozobil, there are some precautions you must take. Regular visits to your doctor are important in order to keep track on your progress and check if the medicine is working properly. Checking your blood for any signs of unwanted effects may be required.

Using this drug is harmful to the unborn baby, so it is important to use an effective birth control method to keep you from getting pregnant.

Tell your doctor right away if you get pregnant while using this medicine.

Do not use this drug if you are breastfeeding.

If you experience having pain in the upper left part of the abdomen or the tip of your left shoulder, tell your doctor immediately. These symptoms could mean the drug has affected your spleen.

If you have allergic reactions, or if you experience:

  • slow heartbeat
  • cold sweats
  • severe and unusual weakness
  • confusion, or faintness
  • dizziness, or lightheadedness when getting up from a sitting or lying position after you get the injection

call your doctor at once.

Some patients may have:

After this medicine is administered your doctor may advise you on how to control or minimize the side effects.

5 Potential Side Effects

While not all people taking Mozobil may suffer from these side effects,you may need to call your doctor if any of these are present:

  • Bleeding gums
  • Itching
  • Crawling, burning,"pins and needles", numbness, or tingling sensations
  • deep, dark purple bruise
  • Blood collecting under the skin
  • coughing up blood
  • the feeling of heat
  • Irritation
  • hives or welts
  • swallowing or breathing difficulties
  • dizziness
  • Flushing
  • headache
  • paralysis
  • hard lump
  • red or black, tarry stools
  • increased menstrual flow
  • vaginal bleeding
  • nosebleeds
  • pain
  • Swelling
  • prolonged bleeding from cuts
  • red or dark brown urine
  • skin rash
  • unusually warm skin
  • Chills
  • confusion
  • cold sweats

Some of the side effects may take place and may not need special medical attention and usually go away as the body adjusts to the medicine during treatment.

Some patients may experience other side effects not listed above. If you want to report side effects, you may do so by calling the FDA at 1-800-FDA-1088.

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