1 What is Myleran?

Brand: Myleran

Generic: Busulfan

Myleran is a drug used in the treatment of chronic myelogenous (myeloid, myelocytic, granulocytic) leukemia. This drug is available as a tablet containing busulfan 2 milligrams.


You should read the product information leaflet before using this medication. If you have any questions, ask your doctor or pharmacist.

This medication should be taken by mouth as instructed by your doctor. Do not crush or chew the drug because it may diminish its effects. This medication should be taken with a full glass of water unless your doctor tells you otherwise. You should swallow the drug whole.

Your dosage is based on your medical condition and the way you will respond to treatment. Take this drug regularly to experience the most benefits. You should also take this drug at the same time each day.

If you miss a dose, use it as soon as you remember. Continue to use it as prescribed by your doctor or as stated on the package label.


Myleran may interact with medications such as:

  • Acetaminophen
  • Itraconazole
  • Metronidazole
  • Thioguanine
  • Bupropion
  • Tramadol
  • Phenothiazines (such as thioridazine)
  • Theophylline
  • Tricyclic antidepressants (such as amitriptyline)

Side Effects:

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking this medication, tell your doctor or pharmacist if you have the following:

  • Allergy to busulfan
  • Blood/bone marrow disorders (such as bone marrow suppression, neutropenia, thrombocytopenia, anemia)
  • Brain disorders (such as seizures, head injury)
  • Pregnancy or lactation

2 Related Clinical Trials