1 What is Naldecon?

Brand: Naldecon, Uni Decon, Naldelate, Nalgest, Nalphen, Nalspan, Prop- A- Hist, Sinucon, West Decon

Generic: Chlorphineramine, Phenyltoloxamine, Phenylephrine and Phenylpropanolamine

Naldecon is an anti-allergy/antihistamine and decongestant drug, used to treat symptoms of allergies, common cold, and hay fever. This is a drug combination of chlorphineramine, phenyltoloxamine, phenylephrine and phenylpropanolamine.

Chlorphineramine and phenyltoloxamine are the anti- allergy or antihistamine components of Naldecon. These drugs inhibit the effect of histamine, a natural substance produced by the body during an allergic reaction, to relieve symptoms such as itchiness, sneezing, runny nose and watery eyes.

Phenylephrine and phenylpropanolamine are the decongestant components of Naldecon. These drugs constrict or shrink the dilated blood vessels in the nasal passages to relieve nasal congestion or stuffy nose. Consequently, these medications make breathing more comfortable and easy.


Read your medication guide and follow your doctor’s prescription at all times.

  • Take Naldecon orally/ by mouth per doctor’s prescription.
  • Do not break, chew or crush sustained- release tablet form of Naldecon to prevent releasing the content of this medication all at once, which may intensify side effects.
  • Use a standard medicine cup/ spoon (not household spoon) to obtain the accurate amount for each dose if you are using the liquid preparation of this medication.
  • The dosage depends on your medical condition or treatment response. Do not adjust your dose without your doctor’s recommendation.
  • Avoid alcohol intake and activities that require mental alertness (i.e. driving, operating machinery) because this medication can cause dizziness.
  • Avoid MAO inhibitor drug intake 14 days before or during your Naldecon treatment to prevent serious side effects.
  • Continue taking Naldecon on a regular schedule (same time of the day). Do not stop taking this medication abruptly without consulting your doctor.

Inform your doctor immediately if your condition aggravates or does not improve after 7 consecutive days of treatment.

Take your missed dose as soon as possible. The time interval between doses must not be too close. Otherwise, stick with the regular schedule and leave out the missed dose. Do not double dose to cover up a missed dose. Record your missed dose and inform your doctor immediately if you missed several doses.


Naldecon may interact with:

  • MAO inhibitor medications (i.e. isocarboxazid, phenelzine, tranylcypromine)
  • Antidepressant medicines
  • Other anti- allergy or antihistamine drugs
  • Analgesic or pain relievers
  • Anti- anxiety drugs
  • Anticonvulsant/ anti- seizure medications and
  • Other medications that may contain chlorphineramine, phenyltoloxamine, phenylephrine or phenylpropanolamine.

Some drugs may either lessen the beneficial effects or worsen the side effects of Naldecon. Likewise, Naldecon may make some drugs less efficient or intensify their side effects.

Make sure to inform your doctor about all other drugs you are currently taking or using (prescribed and non-prescribed medications including vitamins, minerals, and herbal products) to check for possible drug interaction with Naldecon.

Never alter the doses of other medications while on Naldecon neither stop nor start any medicine without the doctor’s recommendation.

Side Effects:

There are no side effects known aside from a possible allergic reaction in people who have previous or unknown hypersensitivity to the drug.

Watch out for signs of allergic reactions such as:

  • Rash
  • Itching
  • Swelling


Before taking Naldecon, tell your health care provider if you have/are:

  • Any allergies to any substance, food or medication, particularly to Naldecon, chlorphineramine, phenyltoloxamine, phenylephrine and phenylpropanolamine;
  • Medical history or a present condition such as:

        o MAO inhibitor intake in the past 14 days

        o Kidney disorder

        o Liver disease

        o Diabetes

        o Glaucoma

        o Heart disease

        o High blood pressure or hypertension

        o Thyroid disorder

        o Breathing problems (i.e. emphysema, chronic bronchitis)

        o Prostate enlargement

        o Other problems in urination and

  • Pregnant, planning to get pregnant or currently breastfeeding a baby (Naldecon has no expected harmful effects to the unborn child but it can pass through breast milk that may harm the nursing child. The risks and benefits of using this medication during pregnancy must be discussed well with your doctor.)