1 What is Namzaric?

Brand: Namzaric

Generic: Memantine And Donepezil

Namzaric is used in the treatment of moderate to severe Alzheimer type of dementia.

It works by preventing activity of glutamate in the brain and also increases the amount of acetylcholine in the brain which may reduce symptoms of Alzheimer.

The combination does not cure the Alzheimer disease but it may improve thinking ability, behavior, and functional ability.

It is available in the capsule (delayed release form) and only with your doctor’s prescription.

2 What to Know Before Using

Before using Namzaric, you must know all about the risks and complications associated with it.


Inform your doctor if you are allergic to any food, preservatives, dyes, or had an allergic reaction when you used this drug before.


There are no adequate studies done which prove Memantine and Donepezil harmful effects in children. It is not expected to cause any different effects than adults. However, safety and efficacy have not been established.


This medicine does not cause any different side effects or problem than it does in younger adults. However, it should be used with caution.


It is a category C drug. It is not safe to use in pregnancy. It may cause harm to an unborn baby.

Breast Feeding

The combination of Memantine and Donepezil is not known if it can pass into breast milk or not. If you are using it while nursing, discuss the potential risks with your doctor.

Drug Interactions

Memantine and Donepezil may interact with other drugs. Your doctor should be informed of any other medicines which you are taking. He may want to change the dosage or drug. Some of them are listed below:

  • Amantadine
  • Carbonic anhydrase inhibitors (acetazolamide)
  • Dextromethorphan
  • Ketamine
  • Sodium bicarbonate
  • Brinzolamide
  • Methazolamide
  • Bupropion
  • Aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs) (ibuprofen)
  • Cholinergic agents (bethanechol)
  • Cholinesterase inhibitors (galantamine)
  • Ketoconazole
  • Quinidine
  • Carbamazepine
  • Dexamethasone
  • Phenobarbital
  • Phenytoin
  • Rifampin
  • Anticholinergics (scopolamine)

Other Medical Conditions

Several other conditions may reduce its effectiveness.

Make sure you inform your doctor of conditions such as

3 Proper Usage

Proper usage of Namzaric requires strict adherence to your doctor’s orders. Read the medication guide carefully. Ask your pharmacist if you have any queries.

Take this medicine by mouth with a full glass of water with or without food. Swallow it as a whole, do not crush, chew or break it.

If you have difficulty in swallowing delayed release form of a capsule, you can open and pour it in a small amount of soft food (applesauce), mix it and swallow it without chewing.


It is different for different patients. Dosage mentioned below is an average dose. You must follow your doctor’s instructions.

  • Adults: 1 capsule once a day at bedtime.
  • The dose of children is determined by your doctor.

Missed dose 

If you miss a dose, take it as soon as you remember it. If it almost a time for your next dose skips the missed dose and continue your daily schedule. Doubling the dose is harmful.


Store it at room temperature. Keep it away from children.

4 Precautions to Take

Before using Namzaric, there are some precautions you must take. Your doctor should check your daily progress at regular visits. He may want a blood or urine test to check for unwanted effects.

Tell your doctor or dentist that you take Memantine and Donepezil before you receive any medical or dental care, emergency care, or surgery.

It may cause stomach or bowel bleeding in some patient.

Inform your doctor immediately if you have:

  • bloody or black tarry stools
  • constipation
  • severe stomach pain
  • vomiting of blood or material that looks like coffee grounds

Do not take more than recommended dose of this medicine as an overdose may cause seizures or have an effect on your heart. Signs of overdose are:

  • increased watering of mouth
  • increased sweating
  • low blood pressure
  • muscle weakness
  • severe nausea
  • severe vomiting
  • slow heartbeat
  • troubled breathing

Do not take any other medicine unless it is discussed with your doctor.

5 Potential side effects

As with many medications, there are several potential side effects associated with Namzaric. Some people may experience none or minor side effects.

Consult with your doctor if they become problematic or frequent:

More common are:

Less common are:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

6 Related Clinical Trials